Composite Mucoepidermoid Carcinoma and Columnar Cell Variant of Papillary Carcinoma of the Thyroid: A Case Report and Review of the Literature

被引：10
作者：
Taconet, Sarah [1 ,2 ]
Bosq, Jacques [1 ]
Hartl, Dana [3 ]
Schlumberger, Martin [4 ,5 ]
Leboulleux, Sophie [4 ]
Scoazec, Jean-Yves [1 ,5 ]
Al-Ghuzlan, Abir [1 ,5 ]
机构：
[1] Serv Pathol Morphol, Gustave Roussy Canc Campus, Villejuif, France
[2] Univ Paris Nord Sorbonne Cite, UFR Med Sante Biol Humaine, Bobigny, France
[3] Unite Chirurg Thyroidienne, Gustave Roussy Canc Campus, Villejuif, France
[4] Serv Med Nucl Nancy, Gustave Roussy Canc Campus, Villejuif, France
[5] Univ Paris 11, Univ Paris Saclay, Fac Med, Le Kremlin Bicetre, France
来源：
INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY | 2016年 / 24卷 / 04期
关键词：
mucoepidermoid carcinoma; thyroid carcinoma; columnar cell variant of papillary carcinoma; FOLLICULAR VARIANT; GLAND;
D O I：
10.1177/1066896915626281
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Primary mucoepidermoid carcinoma (MEC) of the thyroid and columnar cell variant of papillary carcinoma of the thyroid (PCT) are uncommon neoplasms. We report the first case of composite MEC and columnar cell variant of PCT. An 86-year-old man consulted for a 47-mm thyroid nodule, cytologically compatible with PCT. Total thyroidectomy was performed. Histological diagnosis, with support of histochemistry and immunohistochemistry, was mixed primary carcinoma of the thyroid, associating an MEC component with predominantly columnar cell variant of PCT. Sixteen months after surgery and external beam radiation therapy, the patient was free of recurrence or distant metastasis. This case report offers an opportunity to highlight the potential pitfalls concerning the interpretation of mucin histochemistry in thyroid tumors.
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收藏
页码：336 / 340
页数：5
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