Comparison of Norwood Shunt Types: Do the Outcomes Differ 6 Years Later?

被引:28
作者
Graham, Eric M. [1 ]
Zyblewski, Sinai C.
Phillips, Jacob W.
Shirali, Girish S.
Bradley, Scott M.
Forbus, Geoffery A.
Bandisode, Varsha M.
Atz, Andrew M.
机构
[1] Med Univ S Carolina, Div Pediat Cardiol, Charleston, SC 29425 USA
关键词
PULMONARY-ARTERY CONDUIT; BLALOCK-TAUSSIG SHUNT; LEFT-HEART SYNDROME; STAGE-I NORWOOD; RIGHT VENTRICLE; 1ST-STAGE PALLIATION; HEMODYNAMICS; INDEXES; IMPACT;
D O I
10.1016/j.athoracsur.2010.03.078
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background. A modification to the Norwood procedure involving a right ventricle-to-pulmonary artery (RV-PA) shunt may improve early postoperative outcomes. Concerns remain about the effect of the right ventriculotomy required with this shunt on long-term ventricular function. Methods. Between January 2000 and April 2005, 76 patients underwent the Norwood procedure, 35 with a modified Blalock-Taussig shunt (mBTS) and 41 with a RV-PA shunt. Patients were monitored until death or September 1, 2009, with an average follow-up of 6.8 years. Cardiac catheterization, echocardiograms, perioperative Fontan courses, and need for cardiac transplantation were compared between groups. Results. Cumulative survival was 63% (22 of 35) in the mBTS group vs 78% (32 of 41) in the RV-PA group (p = 0.14). Pre-Fontan echocardiography revealed poorer ventricular function in RV-PA patients (p = 0.03). Cardiac transplantation was required in 6 of 32 (19%) patients with a prior RV-PA shunt vs 1 of 23 (4%) in the mBTS group (p = 0.06). This results in an almost identical cumulative transplant-free survival between groups; 60% (21 of 35) in the mBTS group and 63% (26 of 41) in the RV-PA group (p = 0.95). Conclusions. Neither shunt offers a clear survival advantage through an average follow-up of 6.8 years. The RV-PA shunt results in impaired late ventricular function that may result in an increased need for cardiac transplantation. (Ann Thorac Surg 2010;90:31-5) (C) 2010 by The Society of Thoracic Surgeons
引用
收藏
页码:31 / 35
页数:5
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