Comparison of Norwood Shunt Types: Do the Outcomes Differ 6 Years Later?

被引:28
作者
Graham, Eric M. [1 ]
Zyblewski, Sinai C.
Phillips, Jacob W.
Shirali, Girish S.
Bradley, Scott M.
Forbus, Geoffery A.
Bandisode, Varsha M.
Atz, Andrew M.
机构
[1] Med Univ S Carolina, Div Pediat Cardiol, Charleston, SC 29425 USA
关键词
PULMONARY-ARTERY CONDUIT; BLALOCK-TAUSSIG SHUNT; LEFT-HEART SYNDROME; STAGE-I NORWOOD; RIGHT VENTRICLE; 1ST-STAGE PALLIATION; HEMODYNAMICS; INDEXES; IMPACT;
D O I
10.1016/j.athoracsur.2010.03.078
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background. A modification to the Norwood procedure involving a right ventricle-to-pulmonary artery (RV-PA) shunt may improve early postoperative outcomes. Concerns remain about the effect of the right ventriculotomy required with this shunt on long-term ventricular function. Methods. Between January 2000 and April 2005, 76 patients underwent the Norwood procedure, 35 with a modified Blalock-Taussig shunt (mBTS) and 41 with a RV-PA shunt. Patients were monitored until death or September 1, 2009, with an average follow-up of 6.8 years. Cardiac catheterization, echocardiograms, perioperative Fontan courses, and need for cardiac transplantation were compared between groups. Results. Cumulative survival was 63% (22 of 35) in the mBTS group vs 78% (32 of 41) in the RV-PA group (p = 0.14). Pre-Fontan echocardiography revealed poorer ventricular function in RV-PA patients (p = 0.03). Cardiac transplantation was required in 6 of 32 (19%) patients with a prior RV-PA shunt vs 1 of 23 (4%) in the mBTS group (p = 0.06). This results in an almost identical cumulative transplant-free survival between groups; 60% (21 of 35) in the mBTS group and 63% (26 of 41) in the RV-PA group (p = 0.95). Conclusions. Neither shunt offers a clear survival advantage through an average follow-up of 6.8 years. The RV-PA shunt results in impaired late ventricular function that may result in an increased need for cardiac transplantation. (Ann Thorac Surg 2010;90:31-5) (C) 2010 by The Society of Thoracic Surgeons
引用
收藏
页码:31 / 35
页数:5
相关论文
共 23 条
[1]   Two-dimensional echocardiographic assessment of right ventricular function as a predictor of outcome in hypoplastic left heart syndrome [J].
Altmann, K ;
Printz, BF ;
Solowiejczyk, DE ;
Gersony, WM ;
Quaegebeur, J ;
Apfel, HD .
AMERICAN JOURNAL OF CARDIOLOGY, 2000, 86 (09) :964-968
[2]   Impact of right ventricle to pulmonary artery conduit on outcome of the modified norwood procedure [J].
Azakie, A ;
Martinez, D ;
Sapru, A ;
Fineman, J ;
Teitel, D ;
Karl, TR .
ANNALS OF THORACIC SURGERY, 2004, 77 (05) :1727-1733
[3]   A contemporary comparison of the effect of shunt type in hypoplastic left heart syndrome on the hemodynamics and outcome at stage 2 reconstruction [J].
Ballweg, Jean A. ;
Dominguez, Troy E. ;
Ravishankar, Chitra ;
Kreutzer, Jacqueline ;
Marino, Bradley S. ;
Bird, Geoffrey L. ;
Gruber, Peter J. ;
Wernovsky, Gil ;
Gaynor, J. William ;
Nicolson, Susan C. ;
Spray, Thomas L. ;
Tabbutt, Sarah .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2007, 134 (02) :297-303
[4]   Hemodynamic status after the Norwood procedure: A comparison of right ventricle-to-pulmonary artery connection versus modified Blalock-Taussig shunt [J].
Bradley, SM ;
Simsic, JM ;
McQuinn, TC ;
Habib, DM ;
Shirali, GS ;
Atz, AM .
ANNALS OF THORACIC SURGERY, 2004, 78 (03) :933-941
[5]   NORMAL ECG STANDARDS FOR INFANTS AND CHILDREN [J].
DAVIGNON, A ;
RAUTAHARJU, P ;
BOISSELLE, E ;
SOUMIS, F ;
MEGELAS, M ;
CHOQUETTE, A .
PEDIATRIC CARDIOLOGY, 1980, 1 (02) :123-131
[6]  
Forbus GA, 2006, J AM COLL CARDIOL, V47, p244A
[7]   Effect of shunt type on echocardiographic indices after initial palliations for hypoplastic left heart syndrome: Blalock-Taussig shunt versus right ventricle-pulmonary artery conduit [J].
Frommelt, Peter C. ;
Sheridan, David C. ;
Mussatto, Kathy A. ;
Hoffman, George M. ;
Ghanayem, Nancy S. ;
Frommelt, Michele A. ;
Tweddell, James S. .
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, 2007, 20 (12) :1364-1373
[8]   Incidence and outcome of cardiopulmonary resuscitation in patients with shunted single ventricle: Advantage of right ventricle to pulmonary artery shunt [J].
Graham, EM ;
Forbus, GA ;
Bradley, SM ;
Shirali, GS ;
Atz, AM .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2006, 131 (05) :E7-E8
[9]  
Graham EM, 2007, CARDIOL YOUNG, V17, P145, DOI 10.1017/S1047951107000133
[10]   Improved early ventricular performance with a right ventricle to pulmonary artery conduit in stage 1 palliation for hypoplastic left heart syndrome: evidence from strain Doppler echocardiography [J].
Hughes, ML ;
Shekerdemian, LS ;
Brizard, CP ;
Penny, DJ .
HEART, 2004, 90 (02) :191-194