Development of a ruthenium-catalyzed asymmetric epoxidation procedure with hydrogen peroxide as the oxidant

被引：136

作者：

Tse, MK

Döbler, C

Bhor, S

Klawonn, M

Mägerlein, W

Hugl, H

Beller, M

机构：

[1] Univ Rostock, Leibniz Inst Organ Katalyse, D-18055 Rostock, Germany

[2] Bayer AG, D-51368 Leverkusen, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 39期

关键词：

asymmetric catalysis; epoxidations; homogeneous catalysis; ruthenium;

D O I：

10.1002/anie.200460528

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Novel pyboxazines and the known pybox ligands are used in the ruthenium-catalyzed asymmetric epoxidation of olefins with H2O 2 (see scheme). This new catalytic system is successful in the conversion of differently substituted aromatic olefins and gives ee values of up to 84%.

引用

页码：5255 / 5260

页数：6

共 126 条

[1] Synthetic applications of nonmetal catalysts for homogeneous oxidations [J].