Yolk sac tumor of endometrium: A case report and literature review

被引：11
作者：
Lin, Shih-Wen [1 ]
Hsieh, Shu-Wei [2 ]
Huang, Shih-Hung [2 ]
Liang, Hung-Shuo [3 ]
Huang, Chia-Yen [1 ,4 ,5 ]
机构：
[1] Cathay Gen Hosp, Gynecol Canc Ctr, Dept Obstet & Gynecol, Taipei, Taiwan
[2] Cathay Gen Hosp, Dept Pathol, Taipei, Taiwan
[3] Sijhih Cathay Gen Hosp, Dept Obstet & Gynecol, New Taipei, Taiwan
[4] Fu Jen Catholic Univ, Sch Med, New Taipei, Taiwan
[5] Natl Chiao Tung Univ, Dept Biol Sci & Technol, Hsinchu, Taiwan
来源：
TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY | 2019年 / 58卷 / 06期
关键词：
Yolk sac tumor; Endometrial cancer; Adjuvant chemotherapy; ENDODERMAL SINUS TUMOR; DIFFERENTIATION; CARCINOMA;
D O I：
10.1016/j.tjog.2019.09.020
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Objective: To report a rare case of endometrial yolk sac tumor (YST) and review published cases of YST of the endometrium. Case report: A 68-year-old female presented with intermittent vaginal spotting for nine months. An endometrial biopsy showed adenocarcinoma. Complete surgical staging operation was performed and the final pathology revealed stage II endometrial yolk sac tumor. The post-operative a-fetoprotein (AFP) level was 133.4 ng/mL. Post-operative adjuvant chemotherapy with bleomycin, etoposide, and cisplatin (BEP) regimen was prescribed for 6 cycles. AFP levels were normal before the fourth cycle of chemotherapy. She is disease free 6 months after completion of therapy. Conclusion: Primary YSTs arising in the endometrium is an extremely rare disease especially in postmenopausal women. Complete surgical staging operation with adjuvant chemotherapy will lead to good outcome in this disease. (C) 2019 Taiwan Association of Obstetrics & Gynecology. Publishing services by Elsevier B.V.
引用
收藏
页码：846 / 848
页数：3
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