Synergistic Bimetallic Catalysis for Carboboration of Unsaturated Hydrocarbons

被引：20

作者：

Rivera-Chao, Eva ^{[1
]}

Fra, Laura ^{[1
]}

Fananas-Mastral, Martin ^{[1
]}

机构：

[1] Univ Santiago de Compostela, Dept Quim Organ, Ctr Singular Invest Quim Biol & Mat Mol CiQUS, Santiago De Compostela 15782, Spain

来源：

SYNTHESIS-STUTTGART | 2018年 / 50卷 / 19期

关键词：

boron; copper; cross-coupling; synergistic catalysis; unsaturated hydrocarbons; palladium; C-C bond formation; C-B bond formation; CROSS-COUPLING REACTIONS; COOPERATIVE PALLADIUM/COPPER CATALYSIS; STEREOSELECTIVE-SYNTHESIS; ALLYLIC ALKYLATION; GRIGNARD-REAGENTS; ENANTIOSELECTIVE ARYLBORATION; ORGANOBORON COMPOUNDS; CONJUGATE ADDITION; INTERNAL ALKYNES; STILLE REACTION;

D O I：

10.1055/s-0037-1610434

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synergistic bimetallic catalysis has become a very efficient tool for the selective carboboration of unsaturated hydrocarbons. This synthetic approach is based on the use of a catalytically generated boron-substituted organocopper nucleophile in a cross-coupling reaction catalyzed by a second transition metal. This way, hydrocarbons can be used as pro-nucleophiles in this type of transformations thus rendering a clean and operationally simple alternative to the traditional cross-coupling methodologies. This review provides a summary of the developments on this topic and discusses both the synthetic utility and mechanisms of these reactions.

引用

页码：3825 / 3832

页数：8

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