A genome-wide association study reveals a QTL influencing caudal supernumerary teats in Holstein cattle

被引:10
|
作者
Joerg, H. [1 ]
Meili, C. [1 ]
Ruprecht, O. [1 ]
Bangerter, E. [1 ]
Burren, A. [1 ]
Bigler, A. [2 ]
机构
[1] Bern Univ Appl Sci, Sch Agr Forest & Food Sci, CH-3052 Zollikofen, Switzerland
[2] Swissherdbook, CH-3052 Zollikofen, Switzerland
关键词
dairy cattle; genetic markers; genomic selection; extra teats; HERITABILITY; FREQUENCY;
D O I
10.1111/age.12215
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
Supernumerary teats represent a common abnormality of the bovine udder. A genome-wide association study was performed based on the proportion of the occurrence of supernumerary teats in the daughters of 1097 Holstein bulls. The heritability of caudal supernumerary teats without mammary gland in this study was 0.604. The largest proportion of the heritability was attributable to BTA 20. The strongest evidence for association was with five SNPs on chromosome 20, referred to as a QTL. The mode of inheritance at this QTL was dominant. These findings reveal that the occurrence of caudal supernumerary teats without mammary gland in Holstein cattle is influenced by a QTL on chromosome 20 and a polygenic part. The data support the high potential of the SNPs in the QTL region as markers for breeding against caudal supernumerary teats.
引用
收藏
页码:871 / 873
页数:3
相关论文
共 50 条
  • [1] Genome-wide association study uncovers four QTL predisposing to supernumerary teats in cattle
    Pausch, Hubert
    Jung, Simone
    Edel, Christian
    Emmerling, Reiner
    Krogmeier, Dieter
    Goetz, Kay-Uwe
    Fries, Ruedi
    ANIMAL GENETICS, 2012, 43 (06) : 689 - 695
  • [2] Genetic parameters and weighted single-step genome-wide association study for supernumerary teats in Holstein cattle
    Wen, H.
    Luo, H.
    Yang, M.
    Augustino, S. M. A.
    Wang, D.
    Mi, S.
    Guo, Y.
    Zhang, Y.
    Xiao, W.
    Wang, Y.
    Yu, Y.
    JOURNAL OF DAIRY SCIENCE, 2021, 104 (11) : 11867 - 11877
  • [3] Genome-wide association study for supernumerary teats in Swiss Brown Swiss Cattle reveals LGR5 as a major gene on chromosome
    Butty, A. M.
    Frischknecht, M.
    Gredler, B.
    Baes, C.
    Neuenschwander, S.
    Moll, J.
    Bieber, A.
    Seefried, F.
    JOURNAL OF ANIMAL SCIENCE, 2016, 94 : 157 - 157
  • [4] Genome-wide association study for longevity in the Holstein cattle population
    Steri, R.
    Moioli, B.
    Catillo, G.
    Galli, A.
    Buttazzoni, L.
    ANIMAL, 2019, 13 (07) : 1350 - 1357
  • [5] Genome-wide association study in colostrum reveals QTL for natural antibodies in Swedish dairy cattle
    Cordero-Solorzano, J. M.
    Wensman, J. J.
    Traven, M.
    Arts, J. A. J.
    Parmentier, H. K.
    Bovenhuis, H.
    de Koning, D. J.
    JOURNAL OF DAIRY SCIENCE, 2019, 102 : 289 - 290
  • [6] A Genome-Wide Association Study Reveals Dominance Effects on Number of Teats in Pigs
    Lopes, Marcos S.
    Bastiaansen, John W. M.
    Harlizius, Barbara
    Knol, Egbert F.
    Bovenhuis, Henk
    PLOS ONE, 2014, 9 (08):
  • [7] A genome-wide association study reveals a locus for bilateral iridal hypopigmentation in Holstein Friesian cattle
    Hollmann, Anne K.
    Bleyer, Martina
    Tipold, Andrea
    Nessler, Jasmin N.
    Wemheuer, Wilhelm E.
    Schuetz, Ekkehard
    Brenig, Bertram
    BMC GENETICS, 2017, 18
  • [8] A genome-wide association study reveals a locus for bilateral iridal hypopigmentation in Holstein Friesian cattle
    Anne K. Hollmann
    Martina Bleyer
    Andrea Tipold
    Jasmin N. Neßler
    Wilhelm E. Wemheuer
    Ekkehard Schütz
    Bertram Brenig
    BMC Genetics, 18
  • [9] SUPERNUMERARY TEATS AND THEIR ASSOCIATION WITH ESTROGEN-INFLUENCED TRAITS IN HOLSTEIN CATTLE
    BECKETT, RC
    LUDWICK, TM
    RADER, ER
    JOURNAL OF DAIRY SCIENCE, 1973, 56 (05) : 640 - 640
  • [10] Genome-Wide Association Study of Conformation Traits in Brazilian Holstein Cattle
    Silva, Emanueli F. P.
    Gaia, Rita C.
    Mulim, Henrique A.
    Pinto, Luis Fernando Batista
    Iung, Laiza H. S.
    Brito, Luiz F.
    Pedrosa, Victor B.
    ANIMALS, 2024, 14 (17):