Recent advances in surface plasmon resonance imaging: detection speed, sensitivity, and portability

被引：132

作者：

Zeng, Youjun ^{[1
]}

Hu, Rui ^{[1
]}

Wang, Lei ^{[1
]}

Gu, Dayong ^{[2
]}

He, Jianan ^{[2
]}

Wu, Shu-Yuen ^{[3
]}

Ho, Ho-Pui ^{[3
]}

Li, Xuejin ^{[1
]}

Qu, Junle ^{[1
]}

Gao, Bruce Zhi ^{[4
,5
]}

Shao, Yonghong ^{[1
]}

机构：

[1] Shenzhen Univ, Key Lab Optoelect Devices & Syst, Minist Educ & Guangdong Prov, Coll Optoelect Engn,Shenzhen Key Lab Sensor Techn, Shenzhen 518060, Peoples R China

[2] Shenzhen Entry Exit Inspect & Quarantine Bur, Shenzhen 518033, Peoples R China

[3] Chinese Univ Hong Kong, Dept Elect Engn, Shatin, Hong Kong, Peoples R China

[4] Clemson Univ, Dept Bioengn, Clemson, SC 29634 USA

[5] Clemson Univ, COMSET, Clemson, SC 29634 USA

来源：

NANOPHOTONICS | 2017年 / 6卷 / 05期

基金：

中国国家自然科学基金;

关键词：

biosensors; surface plasmon resonance; SPR imaging; nanoplasmonics; plasmonics; SPECTRAL INTERFEROMETRY; GOLD NANOPARTICLES; DNA HYBRIDIZATION; PROTEIN ARRAYS; QUANTUM DOTS; SPR SENSOR; BIOSENSOR; RESOLUTION; MICROSCOPY; ENHANCEMENT;

D O I：

10.1515/nanoph-2017-0022

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Surface plasmon resonance (SPR) biosensor is a powerful tool for studying the kinetics of biomolecular interactions because they offer unique real-time and label-free measurement capabilities with high detection sensitivity. In the past two decades, SPR technology has been successfully commercialized and its performance has continuously been improved with lots of engineering efforts. In this review, we describe the recent advances in SPR technologies. The developments of SPR technologies focusing on detection speed, sensitivity, and portability are discussed in details. The incorporation of imaging techniques into SPR sensing is emphasized. In addition, our SPR imaging biosensors based on the scanning of wavelength by a solid-state tunable wavelength filter are highlighted. Finally, significant advances of the vast developments in nanotechnology-associated SPR sensing for sensitivity enhancements are also reviewed. It is hoped that this review will provide some insights for researchers who are interested in SPR sensing, and help them develop SPR sensors with better sensitivity and higher throughput.

引用

页码：1017 / 1030

页数：14

共 113 条

[1] Cellular Analysis and Detection Using Surface Plasmon Resonance Techniques [J].