Functionalization of Synthetic Bone Substitutes

被引：27

作者：

Busch, Andre ^{[1
,2
]}

Jaeger, Marcus ^{[1
,3
]}

Mayer, Constantin ^{[1
]}

Sowislok, Andrea ^{[2
]}

机构：

[1] St Marien Hosp Mulheim Ruhr, Dept Orthoped Trauma & Reconstruct Surg, D-45468 Mulheim, Germany

[2] Univ Duisburg Essen, Univ Hosp Essen, Dept Orthoped & Trauma Surg, D-45147 Essen, Germany

[3] Univ Duisburg Essen, Chair Orthoped & Trauma Surg, D-45147 Essen, Germany

来源：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2021年 / 22卷 / 09期

关键词：

BMP; tissue engineering; implant related infections; antibiotics; MORPHOGENETIC PROTEINS; CHRONIC OSTEOMYELITIS; CONTROLLED-RELEASE; MOLECULAR ASPECTS; CALCIUM-SULFATE; GROWTH-FACTORS; IN-VITRO; VANCOMYCIN; TISSUE; GENTAMICIN;

D O I：

10.3390/ijms22094412

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Bone substitutes have been applied to treat osseous defects for a long time. To prevent implant related infection (IRI) and enhance bone healing functionalized biomaterials, antibiotics and osteoinductive substances have been introduced. This study gives an overview of the current available surface-coated bone substitutes and provides an outlook for future perspectives.

引用

页数：12

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