Ocular manifestations in Dengue fever

被引:45
作者
Siqueira, RC [1 ]
Vitral, NP
Campos, WR
Oréfice, F
Figueiredo, LTM
机构
[1] CERV, Belo Horizonte, MG, Brazil
[2] Univ Sao Paulo, Ribeirao Preto, Brazil
[3] Univ Fed Minas Gerais, Belo Horizonte, MG, Brazil
关键词
Dengue fever; retinal nonperfusion;
D O I
10.1080/092739490500345
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: To report a case of Dengue fever resulting in permanent visual loss in both eye's due to retinal capillary occlusion. Methods: Case report. Results: Severe permanent visual loss occurred in a patient with Dengue fever. Dilated fundus exam showed vascular sheathing with associated retinal hemorrhages at the equator and cotton wool spots in the maculae of both eyes. Fluorescein angiography revealed areas of capillary nonperfusion at the equator and in the macula. The diagnosis of Dengue fever was confirmed by serology detecting IgM antibodies to the Dengue virus. Conclusion: Ocular abnormalities may be seen in patients with Dengue fever, therefore ophthalmoscopy should be performed in patients presenting with severe forms of the disease.
引用
收藏
页码:323 / 327
页数:5
相关论文
共 18 条
[1]   Structures of immature flavivirus particles [J].
Zhang, Y ;
Corver, J ;
Chipman, PR ;
Zhang, W ;
Pletnev, SV ;
Sedlak, D ;
Baker, TS ;
Strauss, JH ;
Kuhn, RJ ;
Rossmann, MG .
EMBO JOURNAL, 2003, 22 (11) :2604-2613
[2]  
Deutman A F, 1979, Klin Monbl Augenheilkd, V175, P429
[3]  
Figueiredo L T, 1990, Bull Pan Am Health Organ, V24, P217
[4]   AN ENZYME-IMMUNOASSAY FOR DENGUE ANTIBODY USING INFECTED CULTURED MOSQUITO CELLS AS ANTIGEN [J].
FIGUEIREDO, LTM ;
SHOPE, RE .
JOURNAL OF VIROLOGICAL METHODS, 1987, 17 (3-4) :191-198
[5]   The Brazilian flaviviruses [J].
Figueiredo, LTM .
MICROBES AND INFECTION, 2000, 2 (13) :1643-1649
[6]  
FIUEIREDO LTM, 2002, DENGUE B WHO, V26
[7]  
Gubler D. J., 1998, EMERG INFECT DIS, V1, P1
[8]  
HALSTEAD SB, 1988, SCIENCE, V239, P476, DOI 10.1126/science.3277268
[9]   A tourist with dengue fever and visual loss [J].
Haritoglou, C ;
Dotse, SD ;
Rudolph, G ;
Stephan, CM ;
Thurau, SR ;
Klauss, V .
LANCET, 2002, 360 (9339) :1070-1070
[10]   SENSITIVITY AND SPECIFICITY OF A UNIVERSAL PRIMER SET FOR THE RAPID DIAGNOSIS OF DENGUE VIRUS-INFECTIONS BY POLYMERASE CHAIN-REACTION AND NUCLEIC-ACID HYBRIDIZATION [J].
HENCHAL, EA ;
POLO, SL ;
VORNDAM, V ;
YAEMSIRI, C ;
INNIS, BL ;
HOKE, CH .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1991, 45 (04) :418-428