共 57 条
Oxidative stress-mediated apoptosis is involved in bisphenol S-induced reproductive toxicity in male C57BL/6 mice
被引:19
作者:

Dai, Wei
论文数: 0 引用数: 0
h-index: 0
机构:
Univ South China, Dept Prevent Med, Hengyang 421001, Peoples R China Univ South China, Dept Prevent Med, Hengyang 421001, Peoples R China

He, Qing-zhi
论文数: 0 引用数: 0
h-index: 0
机构:
Guilin Med Univ, Dept Occupat & Environm Hlth, Guilin, Peoples R China Univ South China, Dept Prevent Med, Hengyang 421001, Peoples R China

Zhu, Bi-qi
论文数: 0 引用数: 0
h-index: 0
机构:
Univ South China, Dept Prevent Med, Hengyang 421001, Peoples R China Univ South China, Dept Prevent Med, Hengyang 421001, Peoples R China

Zeng, Huai-cai
论文数: 0 引用数: 0
h-index: 0
机构:
Univ South China, Dept Prevent Med, Hengyang 421001, Peoples R China
Guilin Med Univ, Dept Occupat & Environm Hlth, Guilin, Peoples R China Univ South China, Dept Prevent Med, Hengyang 421001, Peoples R China
机构:
[1] Univ South China, Dept Prevent Med, Hengyang 421001, Peoples R China
[2] Guilin Med Univ, Dept Occupat & Environm Hlth, Guilin, Peoples R China
关键词:
apoptosis;
bisphenol S;
Fas;
FasL pathway;
oxidative stress;
reproductive toxicity;
UNITED-STATES;
IN-VITRO;
ANALOGS;
EXPOSURE;
EXPRESSION;
IMPAIRS;
DAMAGE;
RATS;
FAS;
BPA;
D O I:
10.1002/jat.4170
中图分类号:
R99 [毒物学(毒理学)];
学科分类号:
100405 ;
摘要:
The reproductive toxicity of bisphenol S (BPS) in male mammals and its possible mechanism are not clear. We investigated the effects and possible mechanism of action of BPS on adult male C57BL/6 mice. We found that exposure to 200-mg/kg BPS resulted in a significant decrease in the sperm count in the caput/corpus and cauda epididymis, significantly decreased sperm motility, and significantly increased the sperm deformity. Histological evaluation revealed that BPS exposure caused a decrease of spermatozoa in the lumen of seminiferous tubules and a reduction in the proportion of Stage VII or VIII seminiferous tubules in the BPS-treated groups. Furthermore, ultrastructure analysis revealed BPS-induced mitochondrial damage and apoptosis in spermatogenic cells. Moreover, BPS exposure-induced oxidative stress in testicular tissues. Further, dUTP-biotin nick end labeling (TUNEL) assay showed that BPS induced the apoptosis of spermatogenic cells in a dose-dependent manner. BPS also significantly upregulated cleaved caspase-8, cleaved caspase-9, cleaved caspase-3, Fas, and FasL and significantly downregulated the Bcl-2/Bax ratio. These results suggest that BPS-induced oxidative stress in the testis and spermatogenic cell apoptosis potentially impairs spermatogenesis and sperm function, which may be the mechanism of the reproductive toxicity of BPS. The Fas/FasL and mitochondrial signal pathways may be involved in BPS-induced oxidative stress-related apoptosis. These results suggest that BPS-induced oxidative stress in the testis and spermatogenic cell apoptosis potentially impairs spermatogenesis and sperm function, which may be the mechanism of the reproductive toxicity of BPS. The Fas/FasL and mitochondrial signal pathways may be involved in BPS-induced oxidative stress-related apoptosis.
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页码:1839 / 1851
页数:13
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- [1] A review on sources and health impacts of bisphenol A[J]. REVIEWS ON ENVIRONMENTAL HEALTH, 2020, 35 (02) : 201 - 210Abraham, Anna论文数: 0 引用数: 0 h-index: 0机构: SRM Inst Sci & Technol, Dept Civil Engn, Kattankulathur 603203, Tamil Nadu, India SRM Inst Sci & Technol, Dept Civil Engn, Kattankulathur 603203, Tamil Nadu, IndiaChakraborty, Paromita论文数: 0 引用数: 0 h-index: 0机构: SRM Inst Sci & Technol, Dept Civil Engn, Kattankulathur 603203, Tamil Nadu, India SRM Inst Sci & Technol, SRM Res Inst, Kattankulathur 603203, Tamil Nadu, India SRM Inst Sci & Technol, Dept Civil Engn, Kattankulathur 603203, Tamil Nadu, India
- [2] 6-Acetoxy Cyperene, a Patchoulane-type Sesquiterpene Isolated from Cyperus rotundus Rhizomes Induces Caspase-dependent Apoptosis in Human Ovarian Cancer Cells[J]. PHYTOTHERAPY RESEARCH, 2015, 29 (09) : 1330 - 1338Ahn, Ji-Hye论文数: 0 引用数: 0 h-index: 0机构: Kyung Hee Univ, Dept Oriental Pharmaceut Sci, Seoul 130701, South Korea Kyung Hee Univ, Dept Life & Nanopharmaceut Sci, Seoul 130701, South Korea Kyung Hee Univ, Dept Oriental Pharmaceut Sci, Seoul 130701, South KoreaLee, Tae-won论文数: 0 引用数: 0 h-index: 0机构: Kyung Hee Univ, Dept Oriental Pharmaceut Sci, Seoul 130701, South Korea Kyung Hee Univ, Dept Oriental Pharmaceut Sci, Seoul 130701, South KoreaKim, Ki-Hee论文数: 0 引用数: 0 h-index: 0机构: Kyung Hee Univ, Dept Oriental Pharmaceut Sci, Seoul 130701, South Korea Kyung Hee Univ, Dept Oriental Pharmaceut Sci, Seoul 130701, South KoreaByun, Hoyong论文数: 0 引用数: 0 h-index: 0机构: Kyung Hee Univ, Dept Oriental Pharmaceut Sci, Seoul 130701, South Korea Kyung Hee Univ, Dept Oriental Pharmaceut Sci, Seoul 130701, South KoreaRyu, Byeol论文数: 0 引用数: 0 h-index: 0机构: Kyung Hee Univ, Dept Life & Nanopharmaceut Sci, Seoul 130701, South Korea Kyung Hee Univ, Dept Pharmaceut Sci, Coll Pharm, Seoul 130701, South Korea Kyung Hee Univ, Dept Oriental Pharmaceut Sci, Seoul 130701, South KoreaLee, Kyung-Tae论文数: 0 引用数: 0 h-index: 0机构: Kyung Hee Univ, Dept Life & Nanopharmaceut Sci, Seoul 130701, South Korea Kyung Hee Univ, Dept Pharmaceut Sci, Coll Pharm, Seoul 130701, South Korea Kyung Hee Univ, Dept Oriental Pharmaceut Sci, Seoul 130701, South KoreaJang, Dae Sik论文数: 0 引用数: 0 h-index: 0机构: Kyung Hee Univ, Dept Life & Nanopharmaceut Sci, Seoul 130701, South Korea Kyung Hee Univ, Dept Pharmaceut Sci, Coll Pharm, Seoul 130701, South Korea Kyung Hee Univ, Dept Oriental Pharmaceut Sci, Seoul 130701, South KoreaChoi, Jung-Hye论文数: 0 引用数: 0 h-index: 0机构: Kyung Hee Univ, Dept Oriental Pharmaceut Sci, Seoul 130701, South Korea Kyung Hee Univ, Dept Life & Nanopharmaceut Sci, Seoul 130701, South Korea Kyung Hee Univ, Div Mol Biol, Coll Pharm, Seoul 130701, South Korea Kyung Hee Univ, Dept Oriental Pharmaceut Sci, Seoul 130701, South Korea
- [3] Comparative effects of Bisphenol S and Bisphenol A on the development of female reproductive system in rats; a neonatal exposure study[J]. CHEMOSPHERE, 2018, 197 : 336 - 343Ahsan, Nida论文数: 0 引用数: 0 h-index: 0机构: Quaid I Azam Univ, Dept Anim Sci, Reprod Physiol Lab, Islamabad, Pakistan Quaid I Azam Univ, Dept Anim Sci, Reprod Physiol Lab, Islamabad, PakistanUllah, Hizb论文数: 0 引用数: 0 h-index: 0机构: Quaid I Azam Univ, Dept Anim Sci, Reprod Physiol Lab, Islamabad, Pakistan Quaid I Azam Univ, Dept Anim Sci, Reprod Physiol Lab, Islamabad, PakistanUllah, Waheed论文数: 0 引用数: 0 h-index: 0机构: Quaid I Azam Univ, Dept Anim Sci, Reprod Physiol Lab, Islamabad, Pakistan Quaid I Azam Univ, Dept Anim Sci, Reprod Physiol Lab, Islamabad, PakistanJahan, Sarwat论文数: 0 引用数: 0 h-index: 0机构: Quaid I Azam Univ, Dept Anim Sci, Reprod Physiol Lab, Islamabad, Pakistan Quaid I Azam Univ, Dept Anim Sci, Reprod Physiol Lab, Islamabad, Pakistan
- [4] Urinary biomarkers of exposure to 57 xenobiotics and its association with oxidative stress in a population in Jeddah, Saudi Arabia[J]. ENVIRONMENTAL RESEARCH, 2016, 150 : 573 - 581Asimakopoulos, Alexandros G.论文数: 0 引用数: 0 h-index: 0机构: New York State Dept Hlth, Wadsworth Ctr, Empire State Plaza,POB 509, Albany, NY 12201 USA New York State Dept Hlth, Wadsworth Ctr, Empire State Plaza,POB 509, Albany, NY 12201 USAXue, Jingchuan论文数: 0 引用数: 0 h-index: 0机构: New York State Dept Hlth, Wadsworth Ctr, Empire State Plaza,POB 509, Albany, NY 12201 USA New York State Dept Hlth, Wadsworth Ctr, Empire State Plaza,POB 509, Albany, NY 12201 USADe Carvalho, Bruno Pereira论文数: 0 引用数: 0 h-index: 0机构: New York State Dept Hlth, Wadsworth Ctr, Empire State Plaza,POB 509, Albany, NY 12201 USA New York State Dept Hlth, Wadsworth Ctr, Empire State Plaza,POB 509, Albany, NY 12201 USAIyer, Archana论文数: 0 引用数: 0 h-index: 0机构: King Abdulaziz Univ, Prod Bioprod Ind Applicat Res Grp, Vitamin Pharmacogen Res Grp D, Biochem Dept,Fac Sci, Jeddah, Saudi Arabia King Abdulaziz Univ, King Fahd Med Res Ctr, Expt Biochem Unit, Jeddah, Saudi Arabia New York State Dept Hlth, Wadsworth Ctr, Empire State Plaza,POB 509, Albany, NY 12201 USAAbualnaja, Khalid Omer论文数: 0 引用数: 0 h-index: 0机构: King Abdulaziz Univ, Fac Sci, Dept Biochem, Jeddah, Saudi Arabia King Abdulaziz Univ, Bioact Nat Prod Res Grp, Jeddah, Saudi Arabia New York State Dept Hlth, Wadsworth Ctr, Empire State Plaza,POB 509, Albany, NY 12201 USAYaghmoor, Soonham Sami论文数: 0 引用数: 0 h-index: 0机构: King Abdulaziz Univ, King Fahd Med Res Ctr, Expt Biochem Unit, Jeddah, Saudi Arabia King Abdulaziz Univ, Prod Bioprod Ind Applicat Res Grp, Jeddah, Saudi Arabia New York State Dept Hlth, Wadsworth Ctr, Empire State Plaza,POB 509, Albany, NY 12201 USAKumosani, Taha Abdullah论文数: 0 引用数: 0 h-index: 0机构: King Abdulaziz Univ, King Fahd Med Res Ctr, Expt Biochem Unit, Jeddah, Saudi Arabia King Abdulaziz Univ, Prod Bioprod Ind Applicat Res Grp, Fac Sci, Dept Biochem, Jeddah, Saudi Arabia New York State Dept Hlth, Wadsworth Ctr, Empire State Plaza,POB 509, Albany, NY 12201 USAKannan, Kurunthachalam论文数: 0 引用数: 0 h-index: 0机构: New York State Dept Hlth, Wadsworth Ctr, Empire State Plaza,POB 509, Albany, NY 12201 USA King Abdulaziz Univ, King Fahd Med Res Ctr, Expt Biochem Unit, Jeddah, Saudi Arabia King Abdulaziz Univ, Prod Bioprod Ind Applicat Res Grp, Fac Sci, Dept Biochem, Jeddah, Saudi Arabia SUNY Albany, Sch Publ Hlth, Dept Environm Hlth Sci, Albany, NY USA New York State Dept Hlth, Wadsworth Ctr, Empire State Plaza,POB 509, Albany, NY 12201 USA
- [5] Oxidative stress and male infertility[J]. NATURE REVIEWS UROLOGY, 2017, 14 (08) : 470 - 485Bisht, Shilpa论文数: 0 引用数: 0 h-index: 0机构: All India Inst Med Sci, Lab Mol Reprod & Genet, Dept Anat, New Delhi 110029, India All India Inst Med Sci, Lab Mol Reprod & Genet, Dept Anat, New Delhi 110029, IndiaFaiq, Muneeb论文数: 0 引用数: 0 h-index: 0机构: All India Inst Med Sci, Lab Mol Reprod & Genet, Dept Anat, New Delhi 110029, India All India Inst Med Sci, Lab Mol Reprod & Genet, Dept Anat, New Delhi 110029, IndiaTolahunase, Madhuri论文数: 0 引用数: 0 h-index: 0机构: All India Inst Med Sci, Lab Mol Reprod & Genet, Dept Anat, New Delhi 110029, India All India Inst Med Sci, Lab Mol Reprod & Genet, Dept Anat, New Delhi 110029, IndiaDada, Rima论文数: 0 引用数: 0 h-index: 0机构: All India Inst Med Sci, Lab Mol Reprod & Genet, Dept Anat, New Delhi 110029, India All India Inst Med Sci, Lab Mol Reprod & Genet, Dept Anat, New Delhi 110029, India
- [6] Bisphenol A alternatives in thermal paper from the Netherlands, Spain, Sweden and Norway. Screening and potential toxicity[J]. SCIENCE OF THE TOTAL ENVIRONMENT, 2017, 601 : 210 - 221Bjornsdotter, Maria K.论文数: 0 引用数: 0 h-index: 0机构: Vrije Univ Amsterdam, Environm & Hlth, De Boelelaan 1087, NL-1081 HV Amsterdam, Netherlands Univ Cordoba, Inst Fine Chem & Nanochem, Dept Analyt Chem, Marie Curie Bldg Annex,Campus Rabanales, E-14071 Cordoba, Spain Vrije Univ Amsterdam, Environm & Hlth, De Boelelaan 1087, NL-1081 HV Amsterdam, NetherlandsJonker, Willem论文数: 0 引用数: 0 h-index: 0机构: Vrije Univ Amsterdam, Div Bioanalyt Chem, De Boelelaan 1108, NL-1081 HZ Amsterdam, Netherlands Vrije Univ Amsterdam, Environm & Hlth, De Boelelaan 1087, NL-1081 HV Amsterdam, Netherlands论文数: 引用数: h-index:机构:Kool, Jeroen论文数: 0 引用数: 0 h-index: 0机构: Vrije Univ Amsterdam, Div Bioanalyt Chem, De Boelelaan 1108, NL-1081 HZ Amsterdam, Netherlands Vrije Univ Amsterdam, Environm & Hlth, De Boelelaan 1087, NL-1081 HV Amsterdam, NetherlandsBallesteros-Gomez, Ana论文数: 0 引用数: 0 h-index: 0机构: Vrije Univ Amsterdam, Environm & Hlth, De Boelelaan 1087, NL-1081 HV Amsterdam, Netherlands Univ Cordoba, Inst Fine Chem & Nanochem, Dept Analyt Chem, Marie Curie Bldg Annex,Campus Rabanales, E-14071 Cordoba, Spain Vrije Univ Amsterdam, Environm & Hlth, De Boelelaan 1087, NL-1081 HV Amsterdam, Netherlands
- [7] Zearalenone induces apoptosis of rat Sertoli cells through Fas-Fas ligand and mitochondrial pathway[J]. ENVIRONMENTAL TOXICOLOGY, 2019, 34 (04) : 424 - 433Cai, Guodong论文数: 0 引用数: 0 h-index: 0机构: Yangzhou Univ, Coll Vet Med, 12 Wenhui East Rd, Yangzhou 225009, Jiangsu, Peoples R China Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou, Jiangsu, Peoples R China Yangzhou Univ, Minist Educ China, Joint Int Res Lab Agr & Agriprod Safety, Yangzhou, Jiangsu, Peoples R China Yangzhou Univ, Coll Vet Med, 12 Wenhui East Rd, Yangzhou 225009, Jiangsu, Peoples R ChinaSi, Mengxue论文数: 0 引用数: 0 h-index: 0机构: Yangzhou Univ, Coll Vet Med, 12 Wenhui East Rd, Yangzhou 225009, Jiangsu, Peoples R China Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou, Jiangsu, Peoples R China Yangzhou Univ, Coll Vet Med, 12 Wenhui East Rd, Yangzhou 225009, Jiangsu, Peoples R ChinaLi, Xi论文数: 0 引用数: 0 h-index: 0机构: Yangzhou Univ, Coll Vet Med, 12 Wenhui East Rd, Yangzhou 225009, Jiangsu, Peoples R China Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou, Jiangsu, Peoples R China Yangzhou Univ, Coll Vet Med, 12 Wenhui East Rd, Yangzhou 225009, Jiangsu, Peoples R ChinaZou, Hui论文数: 0 引用数: 0 h-index: 0机构: Yangzhou Univ, Coll Vet Med, 12 Wenhui East Rd, Yangzhou 225009, Jiangsu, Peoples R China Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou, Jiangsu, Peoples R China Yangzhou Univ, Coll Vet Med, 12 Wenhui East Rd, Yangzhou 225009, Jiangsu, Peoples R ChinaGu, Jianhong论文数: 0 引用数: 0 h-index: 0机构: Yangzhou Univ, Coll Vet Med, 12 Wenhui East Rd, Yangzhou 225009, Jiangsu, Peoples R China Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou, Jiangsu, Peoples R China Yangzhou Univ, Coll Vet Med, 12 Wenhui East Rd, Yangzhou 225009, Jiangsu, Peoples R ChinaYuan, Yan论文数: 0 引用数: 0 h-index: 0机构: Yangzhou Univ, Coll Vet Med, 12 Wenhui East Rd, Yangzhou 225009, Jiangsu, Peoples R China Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou, Jiangsu, Peoples R China Yangzhou Univ, Coll Vet Med, 12 Wenhui East Rd, Yangzhou 225009, Jiangsu, Peoples R ChinaLiu, Xuezhong论文数: 0 引用数: 0 h-index: 0机构: Yangzhou Univ, Coll Vet Med, 12 Wenhui East Rd, Yangzhou 225009, Jiangsu, Peoples R China Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou, Jiangsu, Peoples R China Yangzhou Univ, Coll Vet Med, 12 Wenhui East Rd, Yangzhou 225009, Jiangsu, Peoples R ChinaLiu, Zongping论文数: 0 引用数: 0 h-index: 0机构: Yangzhou Univ, Coll Vet Med, 12 Wenhui East Rd, Yangzhou 225009, Jiangsu, Peoples R China Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou, Jiangsu, Peoples R China Yangzhou Univ, Minist Educ China, Joint Int Res Lab Agr & Agriprod Safety, Yangzhou, Jiangsu, Peoples R China Yangzhou Univ, Coll Vet Med, 12 Wenhui East Rd, Yangzhou 225009, Jiangsu, Peoples R ChinaBian, Jianchun论文数: 0 引用数: 0 h-index: 0机构: Yangzhou Univ, Coll Vet Med, 12 Wenhui East Rd, Yangzhou 225009, Jiangsu, Peoples R China Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou, Jiangsu, Peoples R China Yangzhou Univ, Minist Educ China, Joint Int Res Lab Agr & Agriprod Safety, Yangzhou, Jiangsu, Peoples R China Yangzhou Univ, Coll Vet Med, 12 Wenhui East Rd, Yangzhou 225009, Jiangsu, Peoples R China
- [8] Spermatogonial behavior in marmoset: a new generation, their kinetics and niche[J]. MOLECULAR HUMAN REPRODUCTION, 2018, 24 (06) : 299 - 309Caldeira-Brant, A. L.论文数: 0 引用数: 0 h-index: 0机构: Univ Fed Minas Gerais, ICB, Dept Morfol, Lab Biol Estrutural & Reprod, BR-31270901 Belo Horizonte, MG, Brazil Univ Fed Minas Gerais, ICB, Dept Morfol, Lab Biol Estrutural & Reprod, BR-31270901 Belo Horizonte, MG, BrazilEras-Garcia, L.论文数: 0 引用数: 0 h-index: 0机构: Univ Fed Minas Gerais, ICB, Dept Morfol, Lab Biol Estrutural & Reprod, BR-31270901 Belo Horizonte, MG, Brazil Univ Fed Minas Gerais, ICB, Dept Morfol, Lab Biol Estrutural & Reprod, BR-31270901 Belo Horizonte, MG, BrazilAlves-Freitas, D.论文数: 0 引用数: 0 h-index: 0机构: Univ Fed Minas Gerais, ICB, Dept Morfol, Lab Biol Estrutural & Reprod, BR-31270901 Belo Horizonte, MG, Brazil Univ Fed Minas Gerais, ICB, Dept Morfol, Lab Biol Estrutural & Reprod, BR-31270901 Belo Horizonte, MG, BrazilAlmeida, F. R. C. L.论文数: 0 引用数: 0 h-index: 0机构: Univ Fed Minas Gerais, ICB, Dept Morfol, Lab Biol Estrutural & Reprod, BR-31270901 Belo Horizonte, MG, Brazil Univ Fed Minas Gerais, ICB, Dept Morfol, Lab Biol Estrutural & Reprod, BR-31270901 Belo Horizonte, MG, BrazilChiarini-Garcia, H.论文数: 0 引用数: 0 h-index: 0机构: Univ Fed Minas Gerais, ICB, Dept Morfol, Lab Biol Estrutural & Reprod, BR-31270901 Belo Horizonte, MG, Brazil Univ Fed Minas Gerais, ICB, Dept Morfol, Lab Biol Estrutural & Reprod, BR-31270901 Belo Horizonte, MG, Brazil
- [9] Bisphenol Analogues Other Than BPA: Environmental Occurrence, Human Exposure, and Toxicity-A Review[J]. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2016, 50 (11) : 5438 - 5453Chen, Da论文数: 0 引用数: 0 h-index: 0机构: Jinan Univ, Sch Environm, Guangzhou Key Lab Environm Exposure & Hlth, Guangzhou 510632, Guangdong, Peoples R China Jinan Univ, Guangdong Key Lab Environm Pollut & Hlth, Guangzhou 510632, Guangdong, Peoples R China So Illinois Univ, Cooperat Wildlife Res Lab, Carbondale, IL 62901 USA So Illinois Univ, Dept Zool, Carbondale, IL 62901 USA Jinan Univ, Sch Environm, Guangzhou Key Lab Environm Exposure & Hlth, Guangzhou 510632, Guangdong, Peoples R ChinaKannan, Kurunthachalam论文数: 0 引用数: 0 h-index: 0机构: SUNY Albany, Sch Publ Hlth, Dept Environm Hlth Sci, Wadsworth Ctr,New York State Dept Hlth, Albany, NY 12201 USA Jinan Univ, Sch Environm, Guangzhou Key Lab Environm Exposure & Hlth, Guangzhou 510632, Guangdong, Peoples R ChinaTan, Hongli论文数: 0 引用数: 0 h-index: 0机构: Jinan Univ, Sch Environm, Guangzhou Key Lab Environm Exposure & Hlth, Guangzhou 510632, Guangdong, Peoples R China Jinan Univ, Guangdong Key Lab Environm Pollut & Hlth, Guangzhou 510632, Guangdong, Peoples R China Jinan Univ, Sch Environm, Guangzhou Key Lab Environm Exposure & Hlth, Guangzhou 510632, Guangdong, Peoples R ChinaZheng, Zhengui论文数: 0 引用数: 0 h-index: 0机构: So Illinois Univ, Dept Physiol, Carbondale, IL 62901 USA Jinan Univ, Sch Environm, Guangzhou Key Lab Environm Exposure & Hlth, Guangzhou 510632, Guangdong, Peoples R ChinaFeng, Yong-Lai论文数: 0 引用数: 0 h-index: 0机构: Hlth Canada, Exposure & Biomonitoring Div, Ottawa, ON K1A 0L2, Canada Jinan Univ, Sch Environm, Guangzhou Key Lab Environm Exposure & Hlth, Guangzhou 510632, Guangdong, Peoples R ChinaWu, Yan论文数: 0 引用数: 0 h-index: 0机构: So Illinois Univ, Cooperat Wildlife Res Lab, Carbondale, IL 62901 USA So Illinois Univ, Dept Zool, Carbondale, IL 62901 USA Jinan Univ, Sch Environm, Guangzhou Key Lab Environm Exposure & Hlth, Guangzhou 510632, Guangdong, Peoples R ChinaWidelka, Margaret论文数: 0 引用数: 0 h-index: 0机构: So Illinois Univ, Cooperat Wildlife Res Lab, Carbondale, IL 62901 USA So Illinois Univ, Dept Zool, Carbondale, IL 62901 USA Jinan Univ, Sch Environm, Guangzhou Key Lab Environm Exposure & Hlth, Guangzhou 510632, Guangdong, Peoples R China
- [10] Prenatal PFOS exposure induces oxidative stress and apoptosis in the lung of rat off-spring[J]. REPRODUCTIVE TOXICOLOGY, 2012, 33 (04) : 538 - 545Chen, Tian论文数: 0 引用数: 0 h-index: 0机构: Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Minist Educ,Key Lab Environm & Hlth, Wuhan 430030, Peoples R China Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Minist Educ,Key Lab Environm & Hlth, Wuhan 430030, Peoples R ChinaZhang, Ling论文数: 0 引用数: 0 h-index: 0机构: Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Minist Educ,Key Lab Environm & Hlth, Wuhan 430030, Peoples R China Wuhan Univ Sci & Technol, Coll Med, Dept Prevent Med, Wuhan 430065, Peoples R China Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Minist Educ,Key Lab Environm & Hlth, Wuhan 430030, Peoples R ChinaYue, Jun-qiu论文数: 0 引用数: 0 h-index: 0机构: Hubei Canc Hosp, Dept Pathol, Wuhan 430079, Peoples R China Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Minist Educ,Key Lab Environm & Hlth, Wuhan 430030, Peoples R ChinaLv, Zi-quan论文数: 0 引用数: 0 h-index: 0机构: Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Minist Educ,Key Lab Environm & Hlth, Wuhan 430030, Peoples R China Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Minist Educ,Key Lab Environm & Hlth, Wuhan 430030, Peoples R ChinaXia, Wei论文数: 0 引用数: 0 h-index: 0机构: Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Minist Educ,Key Lab Environm & Hlth, Wuhan 430030, Peoples R China Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Minist Educ,Key Lab Environm & Hlth, Wuhan 430030, Peoples R ChinaWan, Yan-jian论文数: 0 引用数: 0 h-index: 0机构: Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Minist Educ,Key Lab Environm & Hlth, Wuhan 430030, Peoples R China Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Minist Educ,Key Lab Environm & Hlth, Wuhan 430030, Peoples R ChinaLi, Yuan-yuan论文数: 0 引用数: 0 h-index: 0机构: Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Minist Educ,Key Lab Environm & Hlth, Wuhan 430030, Peoples R China Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Minist Educ,Key Lab Environm & Hlth, Wuhan 430030, Peoples R ChinaXu, Shun-qing论文数: 0 引用数: 0 h-index: 0机构: Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Minist Educ,Key Lab Environm & Hlth, Wuhan 430030, Peoples R China Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Minist Educ,Key Lab Environm & Hlth, Wuhan 430030, Peoples R China