Synthesis of 7-membered cyclic oxamides: Novel HIV-1 protease inhibitors

被引：28

作者：

Jadhav, PK

Man, HW

机构：

[1] Du Pont Merck Pharmaceutical Company, Chem. and Phys. Sciences Department, Experimental Station, Wilmington, DE 19880-0500

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 08期

关键词：

D O I：

10.1016/0040-4039(96)00013-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An intermediate with three chiral centers, constructed by two key reactions viz. asymmetric allylboration and Sharpless epoxidation, has been used for the synthesis of novel 7-membered cyclic oxamides.

引用

页码：1153 / 1156

页数：4

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