Dictazoles: Potential Vinyl Cyclobutane Biosynthetic Precursors to the Dictazolines

被引：38

作者：

Dai, Jingqiu ^{[1
]}

Jimenez, Jorge I. ^{[4
]}

Kelly, Michelle ^{[3
]}

Williams, Philip G. ^{[1
,2
]}

机构：

[1] Univ Hawaii Manoa, Dept Chem, Honolulu, HI 96822 USA

[2] Canc Res Ctr Hawaii, Honolulu, HI 96813 USA

[3] Natl Inst Water & Atmospher Res Ltd, Natl Ctr Aquat Biodivers & Biosecur, Auckland, New Zealand

[4] AgraQuest Inc, Davis, CA 95618 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2010年 / 75卷 / 07期

关键词：

PYRROLE-IMIDAZOLE ALKALOIDS; SCEPTRIN; AGELIFERIN;

D O I：

10.1021/jo902566n

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report here the isolation of five new compounds, dictazoles A and B (1 and 2) and dictazolines C-E (5-7). Evidence is presented for the direct conversion of the cyclobutyl analogue 1 to its cyclohexyl constitutional isomer 5 via a vinyl cyclobutane rearrangement.

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收藏

页码：2399 / 2402

页数：4

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