Hepatobiliary phase liver MR imaging findings after Oxaliplatin-based chemotherapy in cancer patients

被引:17
作者
Unal, Emre [1 ]
Karaosmanoglu, Ali Devrim [1 ]
Ozmen, Mustafa Nasuh [1 ]
Akata, Deniz [1 ]
Karcaaltincaba, Musturay [1 ]
机构
[1] Hacettepe Univ, Dept Radiol, Liver Imaging Team, Sch Med, TR-06100 Ankara, Turkey
关键词
Sinusoidal obstruction syndrome; Oxaliplatin; FNH-like lesion; Colorectal cancer; Gd-EOB-DTPA; Hepatobiliary phase; Liver MRI; FOCAL NODULAR HYPERPLASIA; SINUSOIDAL OBSTRUCTION SYNDROME; BENIGN HEPATOCELLULAR NODULES; PREOPERATIVE CHEMOTHERAPY; REGENERATIVE HYPERPLASIA; PATHOLOGICAL CORRELATION; SIGNAL INTENSITY; METASTASES; FEATURES; HEPATECTOMY;
D O I
10.1007/s00261-018-1482-7
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
To describe Gd-EOB-DTPA-enhanced liver MR imaging findings in colon and rectal cancer patients who received Oxaliplatin. Spectrum of hepatobiliary phase imaging findings include diffuse heterogeneous dysfunction, macronodular and micronodular FNH-like lesions, and coexistence of periportal increased liver function with FNH-like lesions. Differentiation of these benign lesions from metastasis is crucial to avoid biopsy in patients with colorectal cancers and may allow better understanding of sinusoidal obstruction syndrome pathophysiology and regenerative response of liver.
引用
收藏
页码:2321 / 2328
页数:8
相关论文
共 36 条
[1]   Liver histology and surgical outcomes after preoperative chemotherapy with fluorouracil plus oxaliplatin in colorectal cancer liver metastases [J].
Aloia, Thomas ;
Sebagh, Mylene ;
Plasse, Marylene ;
Karam, Vincent ;
Levi, Francis ;
Giacchetti, Sylvie ;
Azoulay, Daniel ;
Bismuth, Henri ;
Castaing, Denis ;
Adam, Rene .
JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (31) :4983-4990
[2]   Oxaliplatin-related sinusoidal obstruction syndrome mimicking metastatic liver tumors [J].
Arakawa, Yusuke ;
Shimada, Mitsuo ;
Utsunomya, Tohru ;
Imura, Satoru ;
Morine, Yuji ;
Ikemoto, Testuya ;
Hanaoka, Jun ;
Sugimoto, Koji ;
Bando, Yoshimi .
HEPATOLOGY RESEARCH, 2013, 43 (06) :685-689
[3]   Focal nodular hyperplasia of the liver in longterm survivors of neuroblastoma How much diagnostic imaging is necessary? [J].
Benz-Bohm, Gabriele ;
Hero, Barbara ;
Gossmann, Axel ;
Simon, Thorsten ;
Koerber, Friederike ;
Berthold, Frank .
EUROPEAN JOURNAL OF RADIOLOGY, 2010, 74 (03) :E2-E6
[4]   Hepatic focal nodular hyperplasia in children previously treated for a solid tumor - Incidence, risk factors, and outcome [J].
Bouyn, CID ;
Leclere, J ;
Raimondo, G ;
le Pointe, HD ;
Couanet, D ;
Valteau-Couanet, D ;
Hartmann, O .
CANCER, 2003, 97 (12) :3107-3113
[5]   Imaging of Hepatic Focal Nodular Hyperplasia: Pictorial Review and Diagnostic Strategy [J].
Burgio, Marco Dioguardi ;
Ronot, Maxime ;
Salvaggio, Giuseppe ;
Vilgrain, Valerie ;
Brancatelli, Giuseppe .
SEMINARS IN ULTRASOUND CT AND MRI, 2016, 37 (06) :511-524
[6]   Clinical and Imaging Features of Focal Nodular Hyperplasia in Children [J].
Cha, Dong Ik ;
Yoo, So-Young ;
Kim, Ji Hye ;
Jeon, Tae Yeon ;
Eo, Hong .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2014, 202 (05) :960-965
[7]   Oxaliplatin-induced sinusoidal obstruction syndrome mimicking metastatic colon cancer in the liver [J].
Choi, Jung-Hye ;
Won, Young-Woong ;
Kim, Hyun Sung ;
Oh, Young-Ha ;
Lim, Sanghyeok ;
Kim, Han-Joon .
ONCOLOGY LETTERS, 2016, 11 (04) :2861-2864
[8]   Multiple focal nodular hyperplasias induced by oxaliplatin-based chemotherapy [J].
Donadon, Matteo ;
Di Tommaso, Luca ;
Roncalli, Massimo ;
Torzilli, Guido .
WORLD JOURNAL OF HEPATOLOGY, 2013, 5 (06) :340-344
[9]   Ring-like enhancement of focal nodular hyperplasia with hepatobiliary-phase Gd-EOB-DTPA-enhanced magnetic resonance imaging: radiological-pathological correlation [J].
Fujiwara, Hiroyasu ;
Sekine, Shigeki ;
Onaya, Hiroaki ;
Shimada, Kazuaki ;
Mikata, Rintaro ;
Arai, Yasuaki .
JAPANESE JOURNAL OF RADIOLOGY, 2011, 29 (10) :739-743
[10]   Fatty liver: Imaging patterns and pitfalls [J].
Hamer, Okka W. ;
Aguirre, Diego A. ;
Casola, Giovanna ;
Lavine, Joel E. ;
Woenckhaus, Matthias ;
Sirlin, Claude B. .
RADIOGRAPHICS, 2006, 26 (06) :1637-1653