Drug-induced movement disorders

被引：29
作者：
Diederich, NJ
Goetz, CG
机构：
[1] Ctr Hosp Luxembourg, Dept Neurosci, L-1210 Luxembourg, Luxembourg
[2] Rush Presbyterian St Lukes Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USA
来源：
NEUROLOGIC CLINICS | 1998年 / 16卷 / 01期
关键词：
D O I：
10.1016/S0733-8619(05)70370-4
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Drug-induced movement disorders are often unrecognized, especially when not due to dopamine receptor blockers. This review discusses acute, subacute, and chronic syndromes. Pathophysiology relates almost always to dopaminergic transmission. Patient-dependent vulnerability and drug-dependent sensitivity are contributing factors. Young patients are more prone to acute reactions, and tardive or chronic conditions are more frequent in the elderly. Subclinical Parkinsonism can be unmasked by medication exposure. Treatment of tardive dyskinesia remains a challenging task for the clinician, but novel antipsychotics and dopamine depleting agents can be beneficial.
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页码：125 / +
页数：16
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