Increasing Incidence of Early-Onset Colorectal Cancer

被引：343

作者：

Sinicrope, Frank A. ^{[1
,2
]}

机构：

[1] Mayo Clin, Mayo Comprehens Canc Ctr, Dept Oncol, Alix Sch Med, Rochester, MN USA

[2] Mayo Clin, Mayo Comprehens Canc Ctr, Dept Med, Alix Sch Med, Rochester, MN USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2022年 / 386卷 / 16期

关键词：

SUSCEPTIBILITY GENE-MUTATIONS; MISMATCH-REPAIR DEFICIENCY; COLON-CANCER; RECTAL-CANCER; YOUNG-ADULTS; RISK; ASSOCIATION; GERMLINE; PREVALENCE; HEALTH;

D O I：

10.1056/NEJMra2200869

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Early-Onset Colorectal CancerEarly-onset disease (at <50 years of age) accounts for 10% of colorectal cancer cases, and the incidence is increasing, particularly in high-income countries. Patients often present with advanced disease in the left colon. One in six patients has deficient DNA mismatch repair. Screening is now recommended to begin at 45 years of age.

引用

页码：1547 / 1558

页数：12

共 90 条

[1] Western diet induces a shift in microbiota composition enhancing susceptibility to Adherent-Invasive E. coli infection and intestinal inflammation [J].

Agus, Allison ;

Denizot, Jeremy ;

Thevenot, Jonathan ;

Martinez-Medina, Margarita ;

Massier, Sebastien ;

Sauvanet, Pierre ;

Bernalier-Donadille, Annick ;

Denis, Sylvain ;

Hofman, Paul ;

Bonnet, Richard ;

Billard, Elisabeth ;

Barnich, Nicolas .

SCIENTIFIC REPORTS, 2016, 6

[2] Physical activity, mediating factors and risk of colon cancer: insights into adiposity and circulating biomarkers from the EPIC cohort [J].

Aleksandrova, Krasimira ;

Jenab, Mazda ;

Leitzmann, Michael ;

Bueno-de-Mesquita, Bas ;

Kaaks, Rudolf ;

Trichopoulou, Antonia ;

Bamia, Christina ;

Lagiou, Pagona ;

Rinaldi, Sabina ;

Freisling, Heinz ;

Carayol, Marion ;

Pischon, Tobias ;

Drogan, Dagmar ;

Weiderpass, Elisabete ;

Jakszyn, Paula ;

Overvad, Kim ;

Dahm, Christina C. ;

Tjonneland, Anne ;

Bouton-Ruault, Marie-Christine ;

Kuehn, Tilman ;

Peppa, Eleni ;

Valanou, Elissavet ;

La Vecchia, Carlo ;

Palli, Domenico ;

Panico, Salvatore ;

Sacerdote, Carlotta ;

Agnoli, Claudia ;

Tumino, Rosario ;

May, Anne ;

van Vulpen, Jonna ;

Borch, Kristin Benjaminsen ;

Oyeyemi, Sunday Oluwafemi ;

Ramon Quiros, J. ;

Bonet, Catalina ;

Sanchez, Maria-Jose ;

Dorronsoro, Miren ;

Navarro, Carmen ;

Barricarte, Aurelio ;

van Guelpen, Bethany ;

Wennberg, Patrik ;

Key, Timothy J. ;

Khaw, Kay-Tee ;

Wareham, Nicholas ;

Assi, Nada ;

Ward, Heather A. ;

Aune, Dagfinn ;

Riboli, Elio ;

Boeing, Heiner .

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2017, 46 (06) :1823-1835

[3] Metabolic Mediators of the Association Between Adult Weight Gain and Colorectal Cancer: Data From the European Prospective Investigation Into Cancer and Nutrition (EPIC) Cohort [J].

Aleksandrova, Krasimira ;

Schlesinger, Sabrina ;

Fedirko, Veronika ;

Jenab, Mazda ;

Bueno-de-Mesquita, Bas ;

Freisling, Heinz ;

Romieu, Isabelle ;

Pischon, Tobias ;

Kaaks, Rudolf ;

Gunter, Marc J. ;

Dahm, Christina C. ;

Overvad, Kim ;

Rostgaard-Hansen, Agnetha Linn ;

Tjonneland, Anne ;

Trichopoulou, Antonia ;

Bamia, Christina ;

Lagiou, Pagona ;

Agnoli, Claudia ;

Mattiello, Amalia ;

Bradbury, Kathryn ;

Khaw, Kay-Tee ;

Riboli, Elio ;

Boeing, Heiner .

AMERICAN JOURNAL OF EPIDEMIOLOGY, 2017, 185 (09) :751-764

[4] To Screen or Not to Screen Adults 45-49 Years of Age: That is the Question [J].

Anderson, Joseph C. ;

Samadder, N. Jewel .

AMERICAN JOURNAL OF GASTROENTEROLOGY, 2018, 113 (12) :1750-1753

[5] Pembrolizumab in Microsatellite-Instability-High Advanced Colorectal Cancer [J].

Andre, T. ;

Shiu, K-K ;

Kim, T. W. ;

Jensen, B., V ;

Jensen, L. H. ;

Punt, C. ;

Smith, D. ;

Garcia-Carbonero, R. ;

Benavides, M. ;

Gibbs, P. ;

de la Fouchardiere, C. ;

Rivera, F. ;

Elez, E. ;

Bendell, J. ;

Le, D. T. ;

Yoshino, T. ;

Van Cutsem, E. ;

Yang, P. ;

Farooqui, M. Z. H. ;

Marinello, P. ;

Diaz, L. A., Jr. .

NEW ENGLAND JOURNAL OF MEDICINE, 2020, 383 (23) :2207-2218

[6] USPSTF recommends expansion of colorectal cancer screening [J].

不详 .

LANCET GASTROENTEROLOGY & HEPATOLOGY, 2021, 6 (01) :1-1

[7]

[Anonymous], 2022, Cancer statistics center

[8] Changes in colorectal cancer incidence in seven high-income countries: a population-based study [J].

Araghi, Marzieh ;

Soerjomataram, Isabelle ;

Bardot, Aude ;

Ferlay, Jacques ;

Cabasag, Citadel J. ;

Morrison, David S. ;

De, Prithwish ;

Tervonen, Hanna ;

Walsh, Paul M. ;

Bucher, Oliver ;

Engholm, Gerda ;

Jackson, Christopher ;

McClure, Carol ;

Woods, Ryan R. ;

Saint-Jacques, Nathalie ;

Morgan, Eileen ;

Ransom, David ;

Thursfield, Vicky ;

Moller, Bjorn ;

Leonfellner, Suzanne ;

Guren, Marianne G. ;

Bray, Freddie ;

Arnold, Melina .

LANCET GASTROENTEROLOGY & HEPATOLOGY, 2019, 4 (07) :511-518

[9] Cumulative Burden of Colorectal Cancer Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer [J].

Archambault, Alexi N. ;

Su, Yu-Ru ;

Jeon, Jihyoun ;

Thomas, Minta ;

Lin, Yi ;

Conti, David V. ;

Win, Aung Ko ;

Sakoda, Lori C. ;

Lansdorp-Vogelaar, Iris ;

Peterse, Elisabeth F. P. ;

Zauber, Ann G. ;

Duggan, David ;

Holowatyj, Andreana N. ;

Huyghe, Jeroen R. ;

Brenner, Hermann ;

Cotterchio, Michelle ;

Bezieau, Stephane ;

Schmit, Stephanie L. ;

Edlund, Christopher K. ;

Southey, Melissa C. ;

MacInnis, Robert J. ;

Campbell, Peter T. ;

Chang-Claude, Jenny ;

Slattery, Martha L. ;

Chan, Andrew T. ;

Joshi, Amit D. ;

Song, Mingyang ;

Cao, Yin ;

Woods, Michael O. ;

White, Emily ;

Weinstein, Stephanie J. ;

Ulrich, Cornelia M. ;

Hoffmeister, Michael ;

Bien, Stephanie A. ;

Harrison, Tabitha A. ;

Hampe, Jochen ;

Li, Christopher I. ;

Schafmayer, Clemens ;

Offit, Kenneth ;

Pharoah, Paul D. ;

Moreno, Victor ;

Lindblom, Annika ;

Wolk, Alicja ;

Wu, Anna H. ;

Li, Li ;

Gunter, Marc J. ;

Gsur, Andrea ;

Keku, Temitope O. ;

Pearlman, Rachel ;

Bishop, D. Timothy .

GASTROENTEROLOGY, 2020, 158 (05) :1274-+

[10]

Archambault AN., 2021, JNCI CANCER SPECT, V5, ppkab029

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