Non-invasive vagus nerve stimulation (nVNS) as symptomatic treatment of migraine in young patients: a preliminary safety study

被引：34

作者：

Grazzi, Licia ^{[1
,2
]}

Egeo, Gabriella ^{[3
]}

Liebler, Eric ^{[4
]}

Padovan, Anna Maria ^{[5
]}

Barbanti, Piero ^{[3
]}

机构：

[1] Carlo Besta Neurol Inst & Fdn, Headache Ctr, Milan, Italy

[2] C Besta Neurol Inst & Fdn, Headache Unit, Via Celoria 11, I-20133 Milan, Italy

[3] San Raffaele Pisana, Ist Ricovero & Cura Carattere Sci, Dept Neurol Motor & Sensorial Sci, Headache & Pain Unit, Rome, Italy

[4] ElectroCore LLC, Basking Ridge, NJ USA

[5] Kiara Assoc, Turin, Italy

来源：

NEUROLOGICAL SCIENCES | 2017年 / 38卷

关键词：

Young age; Migraine without aura; Symptomatic treatment; nVNS approach; gammaCore device; HEADACHE;

D O I：

10.1007/s10072-017-2942-5

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Recent clinical experiences and clinical trials have demonstrated the safety, tolerability, and efficacy of non-invasive vagus nerve stimulation (nVNS; gammaCore (R)) for the acute and prophylactic treatment of migraine. nVNS has a favorable adverse event profile, making it an attractive option for sensitive patient populations. We explored the safety, tolerability, and efficacy of nVNS as acute migraine treatment in adolescents. A group of adolescent patients suffering from migraine without aura were trained to use gammaCore to manage their migraine attacks. 46.8% of the treated migraine attacks (22/47) were considered successfully treated and did not require any rescue medication. No device-related adverse events were recorded. This preliminary study suggests that nVNS may represent a safe, well-tolerated, and effective for acute migraine treatment in adolescents.

引用

页码：S197 / S199

页数：3

共 15 条

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