Prescription opioid abuse among enrollees into methadone maintenance treatment

被引:201
作者
Rosenblum, Andrew
Parrino, Mark
Schnoll, Sidney H.
Fong, Chunki
Maxwell, Carleen
Cleland, Charles M.
Magura, Stephen
Haddox, J. David
机构
[1] Natl Dev & Res Inst Inc, Inst Treatment & Serv Res, New York, NY 10010 USA
[2] Amer Assoc Treatment Opioid Dependence, New York, NY 10014 USA
[3] Purdue Pharma LP, Stamford, CT 06901 USA
关键词
prescription opioids; methadone maintenance; geography; pain;
D O I
10.1016/j.drugalcdep.2007.02.012
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
A multi-state survey of 5663 opioid dependent persons enrolling in 72 methadone maintenance treatment programs (MMTPs) was conducted to determine the prevalence of prescription opioid (PO) abuse, factors associated with PO abuse and sources for POs. Regions where PO abuse was believed to be prevalent were oversampled; primary opioid was defined as the drug used the most before coming to the MMTP. Among primary heroin abusers, 69% reported abusing POs. Opioid abuse frequencies among primary PO abusers were oxycodone (79%), hydrocodone (67%), methadone (40%), morphine (29%), heroin (13%), hydromorphone (16%), fentanyl (9%) and buprenorphine (1 %). Correlates (p <= .01) of PO abuse, using general estimating equations, were: low urbanicity (MMTPs located in comparatively low population density counties), white ethnicity, no history of injecting primary drug, no previous methadone treatment, younger age, chronic pain, and pain as a reason for enrollment. The most frequent sources of POs were dealer, friend or relative, and doctor's prescription; least frequent were Internet and forged prescription. One-third of PO abusers reported a history of injecting their primary drug. PO abuse is highly prevalent among MMTP patients. Future studies should describe HIV/HCV needle injection practices, characteristics that predict treatment outcomes, and factors that contribute to higher prevalence of persistent pain among PO abusers. (c) 2007 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:64 / 71
页数:8
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