Effectiveness of Ad26.COV2.S and BNT162b2 Vaccines against Omicron Variant in South Africa

被引:69
作者
Gray, Glenda [1 ]
Collie, Shirley [2 ]
Goga, Ameena [1 ]
Garrett, Nigel [3 ]
Champion, Jared [2 ]
Seocharan, Ishen [1 ]
Bamford, Lesley [4 ]
Moultrie, Harry [5 ]
Bekker, Linda-Gail [6 ]
机构
[1] South African Med Res Council, Cape Town, South Africa
[2] Discovery Hlth, Sandton, South Africa
[3] Ctr AIDS Programme Res South Africa, Durban, South Africa
[4] Natl Dept Hlth, Pretoria, South Africa
[5] Natl Inst Communicable Dis, Johannesburg, South Africa
[6] Univ Cape Town, Cape Town, South Africa
关键词
D O I
10.1056/NEJMc2202061
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Vaccine Effectiveness against Omicron in South Africa & nbsp;South Africa has a population with a high baseline level of Covid-19. During the recent surge in the omicron variant, the effectiveness of two doses of the BNT162b2 mRNA vaccine and the Ad26.COV2.S vaccine was assessed. Both vaccines provided a high level of protection against severe Covid-19.
引用
收藏
页码:2243 / 2245
页数:3
相关论文
共 5 条
[1]   Effectiveness of the Ad26.COV2.S vaccine in health-care workers in South Africa (the Sisonke study): results from a single-arm, open-label, phase 3B, implementation study [J].
Bekker, Linda-Gail ;
Garrett, Nigel ;
Goga, Ameena ;
Fairall, Lara ;
Reddy, Tarylee ;
Yende-Zuma, Nonhlanhla ;
Kassanjee, Reshma ;
Collie, Shirley ;
Sanne, Ian ;
Boulle, Andrew ;
Seocharan, Ishen ;
Engelbrecht, Imke ;
Davies, Mary-Ann ;
Champion, Jared ;
Chen, Tommy ;
Bennett, Sarah ;
Mametja, Selaelo ;
Semenya, Mabatlo ;
Moultrie, Harry ;
de Oliveira, Tulio ;
Lessells, Richard John ;
Cohen, Cheryl ;
Jassat, Waasila ;
Groome, Michelle ;
Von Gottberg, Anne ;
Le Roux, Engelbert ;
Khuto, Kentse ;
Barouch, Dan ;
Mahomed, Hassan ;
Wolmarans, Milani ;
Rousseau, Petro ;
Bradshaw, Debbie ;
Mulder, Michelle ;
Opie, Jessica ;
Louw, Vernon ;
Jacobson, Barry ;
Rowji, Pradeep ;
Peter, Jonny G. ;
Takalani, Azwi ;
Odhiambo, Jackline ;
Mayat, Fatima ;
Takuva, Simbarashe ;
Corey, Lawrence ;
Gray, Glenda E. .
LANCET, 2022, 399 (10330) :1141-1153
[2]   Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant [J].
Bernal, Jamie Lopez ;
Andrews, Nick ;
Gower, Charlotte ;
Gallagher, Eileen ;
Simmons, Ruth ;
Thelwall, Simon ;
Stowe, Julia ;
Tessier, Elise ;
Groves, Natalie ;
Dabrera, Gavin ;
Myers, Richard ;
Campbell, Colin N. J. ;
Amirthalingam, Gayatri ;
Edmunds, Matt ;
Zambon, Maria ;
Brown, Kevin E. ;
Hopkins, Susan ;
Chand, Meera ;
Ramsay, Mary .
NEW ENGLAND JOURNAL OF MEDICINE, 2021, 385 (07) :585-594
[3]  
Cele Sandile, 2021, medRxiv, DOI [10.1101/2021.12.08.21267417, 10.1101/2021.12.08.21267417]
[4]   Effectiveness of BNT162b2 Vaccine against Omicron Variant in South Africa [J].
Collie, Shirley ;
Champion, Jared ;
Moultrie, Harry ;
Bekker, Linda-Gail ;
Gray, Glenda .
NEW ENGLAND JOURNAL OF MEDICINE, 2022, 386 (05) :494-496
[5]  
Madhi S., 2021, S AFRICAN POPULATION, DOI [10.1101/2021.12.20.21268096v1, DOI 10.1101/2021.12.20.21268096V1]