Flow-assisted basophil activation tests in immediate drug hypersensitivity: two decades of Antwerp experience

被引：15
作者：
Mangodt, E. A. [1 ]
Van Gasse, A. L. [1 ]
Bastiaensen, A. [1 ]
Decuyper, I. I. [1 ]
Uyttebroek, A. [1 ]
Faber, M. [1 ]
Sabato, V. [1 ]
Bridts, C. H. [1 ]
Hagendorens, M. M. [2 ]
De Clerck, L. S. [1 ]
Ebo, D. G. [1 ]
机构：
[1] Univ Antwerp, Univ Antwerp Hosp, Dept Immunol Allergol Rheumatol, Fac Med & Hlth Sci, B-2610 Antwerp, Belgium
[2] Univ Antwerp, Univ Antwerp Hosp, Dept Pediat, Fac Med & Hlth Sci, B-2610 Antwerp, Belgium
来源：
ACTA CLINICA BELGICA | 2016年 / 71卷 / 01期
关键词：
Allergy; Antibiotics; Basophil activation test (BAT); drug; CD63; CD203c; Curares; HistaFlow; Immediate drug hypersensitivity reaction (IDHR); Opiates; IMMUNOGLOBULIN-E ANTIBODIES; IGE-MEDIATED ANAPHYLAXIS; SKIN-TEST CONCENTRATIONS; IN-VITRO EVALUATION; ALLERGIC REACTIONS; SULFIDOLEUKOTRIENE PRODUCTION; HISTAMINE-RELEASE; CROSS-REACTIVITY; PREDICTIVE-VALUE; DIAGNOSIS;
D O I：
10.1080/17843286.2015.1122871
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The last two decades have witnessed that flow-assisted analysis of in vitro-activated basophils can constitute a valuable adjunct in the in vitro diagnostic approach of immediate drug hypersensitivity reactions (IDHR). This article summarises the current experience with the basophil activation test in the diagnosis of IDHR, with particular focus on allergy to curarising neuromuscular blocking agents, antibiotics (beta-lactams and fluoroquinolones), iodinated radiocontrast media and opiates.
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页码：19 / 25
页数：7
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