Statistical Thermodynamic Properties of Linear Protein Solutions

被引：1

作者：

Li, Li-fen ^{[1
]}

Liang, Xi-xia ^{[1
]}

Li, Qian-zhong ^{[1
]}

机构：

[1] Inner Mongolia Univ, Dept Phys, Hohhot 010021, Peoples R China

来源：

CHINESE JOURNAL OF CHEMICAL PHYSICS | 2010年 / 23卷 / 02期

基金：

中国国家自然科学基金;

关键词：

Chemical potential; Linear protein solution; Chain length; Gibbs function; THERMAL HYSTERESIS ACTIVITY; MACROMOLECULAR SOLUTIONS; ANTIFREEZE PROTEIN; I ANTIFREEZE; SCATTERING; TRANSITIONS; SYSTEMS;

D O I：

10.1088/1674-0068/23/02/180-184

中图分类号：

O64 [物理化学（理论化学）、化学物理学]; O56 [分子物理学、原子物理学];

学科分类号：

070203 ; 070304 ; 081704 ; 1406 ;

摘要：

The thermodynamic properties of linear protein solutions are discussed by a statistical mechanics theory with a lattice model. The numerical results show that the Gibbs function of the solution decreases, and the protein chemical potential is enhanced with increase of the protein concentration for dilute solutions. The influences of chain length and temperature on the Gibbs function of the solution as well as the protein chemical potential are analyzed. As an application of the theory, the chemical potentials of some mutants of type I antifreeze proteins are computed and discussed.

引用

页码：180 / 184

页数：5

共 29 条

[1] Gas-phase processes and measurements of macromolecular properties in solution: On the possibility of false positive and false negative signals of protein unfolding [J].

Abzalimov, Rinat R. ;

Frimpong, Agya K. ;

Kaltashov, Igor A. .

INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2006, 253 (03) :207-216

[2] SYSTEMATIC CORRECTIONS TO FLORY-HUGGINS THEORY - POLYMER SOLVENT VOID SYSTEMS AND BINARY BLEND VOID SYSTEMS [J].

BAWENDI, MG ;

FREED, KF .

JOURNAL OF CHEMICAL PHYSICS, 1988, 88 (04) :2741-2756

[3] Depletion and bridging forces in polymer systems:: Monte Carlo simulations at constant chemical potential [J].

Broukhno, A ;

Jönsson, B ;

Åkesson, T ;

Vorontsov-Velyaminov, PN .

JOURNAL OF CHEMICAL PHYSICS, 2000, 113 (13) :5493-5501

[4]

Chao H, 1996, PROTEIN SCI, V5, P1150

[5] Membrane crystallization of macromolecular solutions [J].

Curcio, E ;

Di Profio, G ;

Drioli, E .

DESALINATION, 2002, 145 (1-3) :173-177

[6] Automated measurement of the static light scattering of macromolecular solutions over a broad range of concentrations [J].

Fernandez, Cristina ;

Minton, Allen P. .

ANALYTICAL BIOCHEMISTRY, 2008, 381 (02) :254-257

[7]

FLORY PJ, 1953, PRINCIPLES POLYM CHE, P495

[8] Lattice cluster theory for pedestrians: The incompressible limit and the miscibility of polyolefin blends [J].

Freed, KF ;

Dudowicz, J .

MACROMOLECULES, 1998, 31 (19) :6681-6690

[9] Studying macromolecular solutions without wall effects by stroboscopic small-angle x-ray scattering [J].

Graceffa, Rita ;

Burghammer, Manfred ;

Davies, Richard J. ;

Ponchut, Cyril ;

Riekel, Christian .

APPLIED PHYSICS LETTERS, 2009, 94 (06)

[10] Solvation thermodynamics in a van der Waals liquid [J].

Graziano, G .

THERMOCHIMICA ACTA, 2003, 399 (1-2) :181-187

← 1 2 3 →