Metal complexes with biologically important ligands, CXXVIII [1].: Palladium(II) complexes with deprotonated peptide esters as N,N′-chelate ligands

Reactions of chloro bridged palladium compounds with di- and tripeptide esters give (Et3P)(Cl)(2)Pd((NH2CHRCONHCHR2CO2CH3)-C-1) and the N,N'-chelate compounds (Et3P)-(Cl)Pd((NH2CH2CONCHRCO2R2)-C-1), [C6H4CH2NMe2(C,N)]Pd(NH2CH2CONCH2CO2Et) and (Et3P)Pd(gly-gly-glyOMe-2H(+)). The structure of (Et3P)(Cl)Pd(gly-alaOMe-H+) was determined by X-ray diffraction analyses. Attempts to form open chain peptides from alpha-amino acid ester in the coordination sphere of palladium(II) are reported.