Head and neck teratoma: From diagnosis to treatment

被引:31
作者
Kadlub, Natacha [1 ,2 ,3 ,4 ]
Touma, Joseph [1 ,2 ]
Leboulanger, Nicolas [4 ,5 ]
Garel, Catherine [6 ]
Soupre, Veronique [1 ,2 ]
L'Hermine, Aurore Coulomb [7 ,8 ]
Vazquez, Marie-Paule [1 ,2 ,3 ,4 ]
Picard, Arnaud [1 ,2 ,3 ,8 ]
机构
[1] Hop Necker Enfants Malad, Serv Chirurg Maxillofaciale & Plast, AP HP, F-75015 Paris, France
[2] MAFACE, Ctr Reference Malad Rares Cavite Buccale, F-75015 Paris, France
[3] INSERM, UMRS872, Equipe Biol Orale Mol 5, F-75006 Paris, France
[4] Univ Paris 05, F-75006 Paris, France
[5] Hop Necker Enfants Malad, AP HP, Serv ORL & Chirurg Cervicofaciale, F-75015 Paris, France
[6] Hop Enfants Armand Trousseau, AP HP, Serv Imagerie Med, F-75012 Paris, France
[7] Hop Enfants Armand Trousseau, AP HP, Serv Anatomopathol & Cytol, F-75012 Paris, France
[8] Univ Paris 06, Fac Med Paris 6, F-75005 Paris, France
关键词
Mature teratoma; Cystic teratoma; Benign teratoma; Head and neck neoplasm; Germ cell neoplasm; Embryonic neoplasm; CERVICAL TERATOMAS; MANAGEMENT; TUMORS; DERMOIDS; ARCHIVES; CHILDREN; AFIP;
D O I
10.1016/j.jcms.2014.04.028
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Introduction: Head and neck teratoma is a rare entity. Its prognosis mostly depends on the risk of neonatal respiratory distress, its extension and potential malignancy. Surgical management must be as complete as possible to avoid recurrences and malignant transformation. The authors present a retrospective analysis of 6 cervicofacial teratomas and a review of the literature. The aim of the study was to analyse prenatal, neonatal and postnatal management of teratoma. Materials and methods: Charts of children presenting with a head and neck teratoma, managed by our maxillofacial and plastic surgery unit, were analysed and antenatal, clinical, biological, radiological and pathological characteristics were collected. Surgical treatment, recurrences and surgical outcomes were analysed. Results: Six patients were included: 2 with a cervical teratoma, 2 with a facial teratoma and 2 with intraoral teratomas. In 2 cases, the lesions were diagnosed antenatally and both patients required neonatal resuscitation. All the patients underwent early surgery, and 3 with complete excisions. All patients with an initial incomplete excision eventually presented a recurrence and therefore second look surgery. No malignant transformation was noted. Conclusion: Early prenatal diagnosis is crucial to neonatal care. Early surgery and meticulous follow-up are critical in the long-term favourable outcome. (C) 2014 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:1598 / 1603
页数:6
相关论文
共 27 条
  • [1] Teratomas of the head and neck region
    Anderson, PJ
    David, DJ
    [J]. JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY, 2003, 31 (06) : 369 - 377
  • [2] Alpha-fetoprotein in the early neonatal period - a large study and review of the literature
    Bader, D
    Riskin, A
    Vafsi, O
    Tamir, A
    Peskin, B
    Israel, N
    Merksamer, R
    Dar, H
    David, M
    [J]. CLINICA CHIMICA ACTA, 2004, 349 (1-2) : 15 - 23
  • [3] TERATOMAS OF THE HEAD AND NECK WITH EMPHASIS ON MALIGNANCY
    BATSAKIS, JG
    ELNAGGAR, AK
    LUNA, MA
    [J]. ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 1995, 104 (06) : 496 - 500
  • [4] Diagnosis and management of cervicofacial congenital teratomas: about 4 cases, literature review and restatement
    Benouaiche, L.
    Couly, G.
    Michel, B.
    Devauchelle, B.
    [J]. ANNALES DE CHIRURGIE PLASTIQUE ESTHETIQUE, 2007, 52 (02): : 114 - 123
  • [5] Hygroma or teratoma? Pitfalls in the management of congenital cystic neck masses
    Clifton, N. J.
    Ross, S. K.
    Gupta, B.
    Gibbin, K. P.
    [J]. INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY EXTRA, 2007, 2 (01) : 61 - 64
  • [6] Fetal tracheolaryngeal airway obstruction: prenatal evaluation by sonography and MRI
    Courtier, Jesse
    Poder, Liina
    Wang, Zhen J.
    Westphalen, Antonio C.
    Yeh, Benjamin M.
    Coakley, Fergus V.
    [J]. PEDIATRIC RADIOLOGY, 2010, 40 (11) : 1800 - 1805
  • [7] GROSFELD JL, 1976, SURGERY, V80, P297
  • [8] CERVICAL TERATOMAS IN THE NEWBORN
    GUNDRY, SR
    WESLEY, JR
    KLEIN, MD
    BARR, M
    CORAN, AG
    [J]. JOURNAL OF PEDIATRIC SURGERY, 1983, 18 (04) : 382 - 386
  • [9] Spectrum of intrapartum management strategies for giant fetal cervical teratoma
    Hirose, S
    Sydorak, RM
    Tsao, K
    Cauldwell, CB
    Newman, KD
    Mychaliska, GB
    Albanese, CT
    Lee, H
    Farmer, DL
    [J]. JOURNAL OF PEDIATRIC SURGERY, 2003, 38 (03) : 446 - 450
  • [10] HOLT GR, 1979, EAR NOSE THROAT J, V58, P520