A furostanol saponin and phytoecdysteroid from roots of Helleborus orientalis

被引：6
作者：
Akin, Sebahat [1 ]
Anil, Huseyin
机构：
[1] Balikesir Univ, Fac Arts & Sci, Dept Chem, Balikesir, Turkey
[2] Ege Univ, Fac Sci, Dept Chem, Izmir, Turkey
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2007年 / 43卷 / 01期
关键词：
Helleborus orientalis; furostanol saponin; phytoecdysteroid;
D O I：
10.1007/s10600-007-0039-8
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A furostanol saponin mixture and a known phytoecdysteroid were isolated from the roots of Helleborus orientalis Lam. Their structures were established as 26-[(beta-D-glucopyranosyl)oxy]-22 alpha-hidroxyfurosta-5,25(27)-dien-1 beta,3 beta,11 alpha-triol (1a), 26-[(beta-D-glucopyranosyl)oxy]-22 alpha-methoxyfurosta-5,25(27)-dien-1 beta,3 beta,11 alpha-triol (1b), and 20-hydroxy-beta-ecdyson-3-O-beta-D-glycoside (2). Acid hydrolysis of 1a,b gave (1 beta,3 beta,11 alpha,22 alpha)-22,26-dimethoxyfurosta-5,25(27)-dien-1,3,11-triol (aglycone 1) and of 2 gave 20-hydroxy-beta-ecdyson (aglycone 2). Their structures were elucidated by spectral analysis.
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页码：90 / 92
页数：3
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