Rho Signaling and Tight Junction Functions

被引：137
作者：
Terry, Steve [1 ]
Nie, Mei [1 ]
Matter, Karl [1 ]
Balda, Maria S. [1 ]
机构：
[1] UCL, Dept Cell Biol, UCL Inst Ophthalmol, London, England
来源：
PHYSIOLOGY | 2010年 / 25卷 / 01期
基金：
英国惠康基金; 英国医学研究理事会; 英国生物技术与生命科学研究理事会;
关键词：
TRANSEPITHELIAL ELECTRICAL-RESISTANCE; BINDING PROTEIN-A; CELL-ADHESION; PARACELLULAR PERMEABILITY; BARRIER FUNCTION; IMMUNOGLOBULIN SUPERFAMILY; ENDOTHELIAL PERMEABILITY; OCCLUDIN PHOSPHORYLATION; EPITHELIAL MORPHOGENESIS; COFILIN PHOSPHORYLATION;
D O I：
10.1152/physiol.00034.2009
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
Tight junctions are heteromeric protein complexes that act as signaling centers by mediating the bidirectional transmission of information between the environment and the cell interior to control paracellular permeability and differentiation. Insight into tight junction-associated signaling mechanisms is of fundamental importance for our understanding of the physiology of epithelia and endothelia in health and disease.
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收藏
页码：16 / 26
页数：11
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