Allergic Rhinitis Environmental Determinants

被引:42
作者
Dunlop, Joan [1 ]
Matsui, Elizabeth [2 ]
Sharma, Hemant P. [3 ]
机构
[1] Childrens Natl Hlth Syst, Div Emergency Med, 111 Michigan Ave NW, Washington, DC 20010 USA
[2] Johns Hopkins Sch Med, Div Pediat Allergy & Immunol, 600 N Wolfe St,CMSC 1102, Baltimore, MD 21287 USA
[3] George Washington Univ, Sch Med & Hlth Sci, Childrens Natl Hlth Syst, Div Allergy & Immunol, 111 Michigan Ave Northwest,Suite W-100A, Washington, DC 20010 USA
关键词
Allergic rhinitis; Environment; Allergen; Sensitization; Risk; CHILDHOOD HAY-FEVER; ENDOTOXIN EXPOSURE; AIRBORNE ENDOTOXIN; IMMUNE-RESPONSE; AIR-POLLUTION; RISK; SENSITIZATION; ASSOCIATION; TRICLOSAN; CHILDREN;
D O I
10.1016/j.iac.2015.12.012
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
The increasing prevalence of allergic rhinitis (AR) seems to be linked to several important environmental factors that interact with underlying genetic predisposition to influence the risk of this disease. This article examines these environmental determinants of AR, and the evidence for their association with disease prevalence. Exposure to a variety of aeroallergens is strongly implicated in the pathogenesis and progression of AR. Other environmental exposures have been suggested to play potential roles in the risk of AR, including bacterial exposure, air pollution, and environmental toxicants.
引用
收藏
页码:367 / +
页数:13
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