Organotin(IV) Carboxylates of Substituted α-Cinnamic Acid, RnSn(OCOC(R2)=CHR1)4 - n: Synthesis, Spectroscopic Characterization and Biological Evaluation

被引：8
|
作者：
Sadiq-ur-Rehman [1 ]
Khan, Bilal Ahmad [1 ]
Chaudhary, Muhammad Aziz [2 ]
Yasin, Khawaja Ansar [1 ]
Ali, Saqib [3 ]
机构：
[1] Univ Azad Jammu & Kashmir, Dept Chem, Muzaffarabad 13100, Pakistan
[2] Mirpur Univ Sci & Technol, Dept Chem, Mirpur, Pakistan
[3] Quaid I Azam Univ, Dept Chem, Islamabad 45320, Pakistan
来源：
HETEROATOM CHEMISTRY | 2015年 / 26卷 / 06期
关键词：
CRYSTAL; NMR; COMPLEXES; ANGLE; C-13;
D O I：
10.1002/hc.21276
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Di- and triorganotin(IV) carboxylates, RnSn(OCOC(R-2)=CHR1)(4-n) (n = 2 and 3; R = Me, Et, n-Bu, Ph; R-1 = 3-CH3O-4-OHC6H3, R-2 = C6H5) were prepared by reacting the corresponding organotin(IV) chloride with the silver salt of the (E)-3-(4-hydroxy-3-methoxyphenyl)2- phenylpropenoic acid. The title compounds were investigated and characterized by elemental analysis, infrared (FT-IR), multinuclear (H-1, C-13, Sn-119) NMR, and mass spectrometry, and possible structures were proposed. The complexes and ligand acid (HL) have been evaluated in vitro against various bacteria and fungi. The results noticed during the biocidal activity screenings proved their in vitro biological potential. They were also tested for cytotoxicity. (C) 2015 Wiley Periodicals, Inc.
引用
收藏
页码：417 / 425
页数：9
相关论文
共 50 条
  • [21] Synthesis, spectroscopic studies and biological applications of organotin(IV) derivatives of 3-[N-(4-nitrophenyl)-amidolpropenoic acid and 3-[N-(4-Nitrophenyl)-amidolpropanoic acid
    Shahid, K
    Shahzadi, S
    Ali, S
    Mazhar, M
    BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2006, 27 (01): : 44 - 52
  • [22] Biological screening, DNA interaction studies, and catalytic activity of organotin( IV) 2-(4-ethylbenzylidene) butanoic acid derivatives: synthesis, spectroscopic characterization, and X-ray structure
    Tariq, Muhammad
    Ali, Saqib
    Muhammad, Niaz
    Shah, Naseer Ali
    Sirajuddin, Muhammad
    Tahir, Muhammad Nawaz
    Khalid, Nasir
    Khan, Muhammad Rashid
    JOURNAL OF COORDINATION CHEMISTRY, 2014, 67 (02) : 323 - 340
  • [23] Organotin(IV) complexes of 2-hydroxyacetophenone-N(4)-cyclohexylthiosemicarbazone (H2dact): Synthesis, spectral characterization, crystal structure and biological studies
    Affan, M. A.
    Salam, M. A.
    Ahmad, Fasihuddin B.
    White, Fraser
    Ali, Hapipah M.
    INORGANICA CHIMICA ACTA, 2012, 387 : 219 - 225
  • [24] Synthesis, spectroscopic studies and biological applications of organotin(IV) derivatives of 3-[N-(4-nitrophenyl)-amido]propenoic acid and 3-[N-(4-Nitrophenyl)-amido]propanoic acid
    Department of Chemistry, Quaid-i-Azam University, Islamabad 45320, Pakistan
    Bull. Korean Chem. Soc., 2006, 1 (44-52):
  • [25] Synthesis, spectroscopic, X-ray crystal structure, biological and DNA interaction studies of organotin(IV) complexes of 2-(4-ethoxybenzylidene) butanoic acid
    Tariq, Muhammad
    Muhammad, Niaz
    Ali, Saqib
    Shirazi, Jafir Hussain
    Tahir, Muhammad Nawaz
    Khalid, Nasir
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2014, 122 : 356 - 364
  • [26] Organotin(IV) complexes of 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid: Synthesis, spectral characterization and biological applications
    K. Shahid
    S. Shahzadi
    S. Ali
    M. H. Bhatti
    K. M. Khan
    Journal of the Iranian Chemical Society, 2005, 2 : 140 - 148
  • [27] Organotin(IV) complexes of 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid: Synthesis, spectral characterization and biological applications
    Shahid, K.
    Shahzadi, S.
    Ali, S.
    Bhatti, M. H.
    Khan, K. M.
    JOURNAL OF THE IRANIAN CHEMICAL SOCIETY, 2005, 2 (02) : 140 - 148
  • [28] Synthesis and spectroscopic characterization of organotin(IV) complexes with 2-benzoylpyridine-N(4)-cyclohexylthiosemicarbazone (HBPCT): X-ray crystal structure of [PhSnCl2(BPCT)]
    Affan, M. A.
    Salam, M. A.
    Ahmad, Fasihuddin B.
    Ismail, J.
    Shamsuddin, Mustaffa B.
    Ali, Hapipah M.
    INORGANICA CHIMICA ACTA, 2011, 366 (01) : 227 - 232
  • [29] Synthesis, spectroscopic characterization, X-ray structures, biological screenings, DNA interaction study and catalytic activity of organotin(IV) 3-(4-flourophenyl)-2-methylacrylic acid derivatives
    Tariq, Muhammad
    Muhammad, Niaz
    Sirajuddin, Muhammad
    Ali, Saqib
    Shah, Naseer Ali
    Khalid, Nasir
    Tahir, Muhammad Nawaz
    Khan, Muhammad Rashid
    JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2013, 723 : 79 - 89
  • [30] SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF 1H-SUBSTITUTED 2, 4, 5-TRIPHENYL IMIDAZOLE DERIVATIVES
    Ajila, E.
    Roy, R. Aniz K.
    Bai, Thara
    INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2018, 5 (08): : 7367 - 7373
12345