Chiral N,N′-dioxide-Yb(III) complexes catalyzed enantioselective hydrophosphonylation of aldehydes

被引：40

作者：

Chen, Weiliang ^{[1
]}

Hui, Yonghai ^{[1
]}

Zhou, Xin ^{[1
]}

Jiang, Jun ^{[1
]}

Cai, Yunfei ^{[1
]}

Liu, Xiaohua ^{[1
]}

Lin, Lili ^{[1
]}

Feng, Xiaoming ^{[1
]}

机构：

[1] Sichuan Univ, Coll Chem, Minist Educ, Key Lab Green Chem & Technol, Chengdu 610064, Peoples R China

来源：

TETRAHEDRON LETTERS | 2010年 / 51卷 / 32期

基金：

中国国家自然科学基金;

关键词：

Asymmetric hydrophosphonylation; Aldehydes; N; '-dioxides; Ytterbium; Hydroxy phosphonates; FRIEDEL-CRAFTS ALKYLATION; LI-BINOL COMPLEX; ASYMMETRIC HYDROPHOSPHONYLATION; AL(SALALEN) COMPLEX; TITANIUM ALKOXIDES; BOND FORMATION; PHOSPHONATES; ALDIMINES; SUBSTITUENTS; INHIBITORS;

D O I：

10.1016/j.tetlet.2010.05.137

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Chiral N,N'-dioxide-Ytterbium(III) complexes promoted the asymmetric addition of diethyl phosphate to aldehydes, giving the corresponding products with good yields and enantioselectivities. The addition of pyridine favored both reactivity and enantioselectivity. A possible catalytic cycle was proposed to explain the mechanism of the asymmetric hydrophosphonylation of aldehydes. (C) 2010 Elsevier Ltd. All rights reserved.

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收藏

页码：4175 / 4178

页数：4

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