Copper-catalyzed cross-coupling reactions of epoxides with gem-diborylmethane: access to γ-hydroxyl boronic esters

被引：50

作者：

Ebrahim-Alkhalil, Ahmed ^{[1
]}

Zhang, Zhen-Qi ^{[1
]}

Gong, Tian-Jun ^{[1
]}

Su, Wei ^{[1
]}

Lu, Xiao-Yu ^{[1
]}

Xiao, Bin ^{[1
]}

Fu, Yao ^{[1
]}

机构：

[1] Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, CAS Key Lab Urban Pollutant Convers, Anhui Prov Key Lab Biomass Clean Energy,iChEM, Hefei 230026, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 27期

关键词：

SECONDARY ALKYL-HALIDES; CONSTRUCTION; DIARYLMETHANES; SP(3)-CARBON; FLUORINATION; AZIRIDINES; REAGENTS;

D O I：

10.1039/c5cc09817c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Herein, we describe a novel copper-catalyzed epoxide opening reaction with gem-diborylmethane. Aliphatic, aromatic epoxides as well as aziridines are converted to the corresponding gamma-pinacolboronate alcohols or amines in moderate to excellent yields. This new reaction provides beneficial applications for classic epoxide substrates as well as interesting gem-diborylalkane reagents.

引用

页码：4891 / 4893

页数：3

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