Trypanosoma cruzi: Adhesion to the host cell and intracellular survival

被引:47
作者
Alves, Maria Julia M. [1 ]
Colli, Walter [1 ]
机构
[1] Univ Sao Paulo, Dept Bioquim, Inst Quim, BR-05508900 Sao Paulo, Brazil
关键词
Trypanosoma cruzi; host-cell invasion; Gp85/trans-sialidase; Tc-85; proteases; intracellular survival;
D O I
10.1080/15216540701200084
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Both invasion of the host cell by T. cruzi and its establishment into the mammalian host are critical steps. In this review, the adhesion step and the intracellular survival in non-professional phagocytes are particularly focused on, with special emphasis on the role of Gp85/trans-sialidase (Gp85/TS) superfamily. Excellent reviews have been published lately, some covering other aspects of T. cruzi-host interaction and will be cited instead of the original articles due to limited number of listed references.
引用
收藏
页码:274 / 279
页数:6
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