Mood state and cerebral metabolism in persons with age-associated memory impairment

被引：2
|
作者：
Cherrier, MM
Small, GW
Komo, S
La Rue, A
机构：
[1] Univ Washington, Sch Med, Dept Psychiat & Behav Sci, GRECC 182B, Seattle, WA 98195 USA
[2] Univ Calif Los Angeles, Sch Med, Neuropsychiat Inst & Hosp, Dept Psychiat & Biobehav Sci, Los Angeles, CA 90024 USA
来源：
PSYCHIATRY RESEARCH-NEUROIMAGING | 1997年 / 76卷 / 2-3期
关键词：
positron emission tomography (PET); age-associated memory impairment (AAMI); visual analogue scale; mood; emotion; asymmetry;
D O I：
10.1016/S0925-4927(97)00045-0
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
People undergoing medical procedures sometimes experience feelings that may influence the results. In this study, we explore the relationship between changes in mood state self-ratings and cerebral glucose metabolism during positron emission tomography (PET) in persons with age-associated memory impairment (mean age 59.4 +/- 9.8 years). Brain regions of interest involved in both mood and memory were examined. Mood ratings of increased boredom correlated significantly with mesial temporal and parietal asymmetry and decreased parietal metabolism. Mood ratings of increased fatigue correlated with basal ganglia asymmetry and the right basal ganglia and left mesial temporal metabolism. These findings suggest that subjective mood state changes during PET may influence metabolism in brain regions implicated in emotion and memory function in people with age-related memory complaints. (C) 1997 Elsevier Science Ireland Ltd.
引用
收藏
页码：67 / 74
页数：8
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