Novel azobenzene derivatives containing a glucopyranoside moiety. Part I: synthesis, characterisation and mutagenic properties

被引:7
作者
Barni, E
Barolo, C
Quagliotto, P
Valldeperas, J
Viscardi, G
机构
[1] Univ Turin, Dipartimento Chim Gen Organ Appl, I-10125 Turin, Italy
[2] Inst Invest Text & Cooperat Ind, Terrassa 08222, Spain
关键词
dyes; azobenzene derivatives; glucopyranosides; thermal analysis; H-1 NMR analysis; Ames test; mutagenicity;
D O I
10.1016/S0143-7208(00)00033-4
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
The synthesis of dimethylaminoazobenzene derivatives containing a beta-D-glucopyranosyl ring is described. Structures have been defined by H-1 NMR techniques, selective decoupling and H-1-H-1 COSY. Differential thermal analysis. (DTA) and thermogravimetry (TG) have been used to describe their thermal behaviour. Genotoxicity (Ames test) comparisons with their p-methoxy counterparts have shown the effect of beta-D-glucopyranosyl on reducing the mutagenicity. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:29 / 36
页数:8
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