OPINION Emerging roles of ATF2 and the dynamic AP1 network in cancer

被引：257

作者：

Lopez-Bergami, Pablo ^{[1
]}

Lau, Eric ^{[2
]}

Ronai, Ze'ev ^{[2
]}

机构：

[1] Inst Biol & Med Expt, RA-1428 Buenos Aires, DF, Argentina

[2] Burnham Inst Med Res, Signal Transduct Program, La Jolla, CA 92037 USA

来源：

NATURE REVIEWS CANCER | 2010年 / 10卷 / 01期

关键词：

ACTIVATING TRANSCRIPTION FACTOR-2; ANCHORAGE-INDEPENDENT GROWTH; C-JUN EXPRESSION; DOMINANT-NEGATIVE MUTANT; ELEMENT-BINDING PROTEIN; SQUAMOUS-CELL CARCINOMA; FACTOR-KAPPA-B; SIGNAL-TRANSDUCTION PATHWAY; EMBRYONIC STEM-CELLS; AMP RESPONSE ELEMENT;

D O I：

10.1038/nrc2681

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Cooperation among transcription factors is central for their ability to execute specific transcriptional programmes. The AP1 complex exemplifies a network of transcription factors that function in unison under normal circumstances and during the course of tumour development and progression. This Perspective summarizes our current understanding of the changes in members of the AP1 complex and the role of ATF2 as part of this complex in tumorigenesis.

引用

页码：65 / 76

页数：12

共 227 条

[1] Preclinical studies of celastrol and acetyl lsogambogic acid in melanoma [J].

Abbas, Sabiha ;

Bhoumik, Anindita ;

Dahl, Russell ;

Vasile, Stefan ;

Krajewski, Stan ;

Cosford, Nicholas D. P. ;

Ronai, Zeev A. .

CLINICAL CANCER RESEARCH, 2007, 13 (22) :6769-6778

[2]

ABDELHAFIZ HAM, 1993, ONCOGENE, V8, P1161

[3] Correlation between c-Jun and human papillomavirus in oral premalignant and malignant lesions [J].

Acay, Renata Rodrigues ;

dos Santos, Elisa ;

Machado de Sousa, Suzana Orsini .

ORAL ONCOLOGY, 2008, 44 (07) :698-702

[4] Mitogen regulated induction of FRA-1 proto-oncogene is controlled by the transcription factors binding to both serum and TPA response elements [J].

Adiseshaiah, P ;

Peddakama, S ;

Zhang, Q ;

Kalvakolanu, DV ;

Reddy, SP .

ONCOGENE, 2005, 24 (26) :4193-4205

[5]

ADUNYAH SE, 1995, BBA-GENE STRUCT EXPR, V1263, P123

[6] Transcription factor JunD, deprived of menin, switches from growth suppressor to growth promoter [J].

Agarwal, SK ;

Novotny, EA ;

Crabtree, JS ;

Weitzman, JB ;

Yaniv, M ;

Burns, AL ;

Chandrasekharappa, SC ;

Collins, FS ;

Spiegel, AM ;

Marx, SJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (19) :10770-10775

[7] Epigenetic determination of a cell-specific gene expression program by ATF-2 and the histone variant macroH2A [J].

Agelopoulos, Marios ;

Thanos, Dimitris .

EMBO JOURNAL, 2006, 25 (20) :4843-4853

[8] Inflammation and cancer: how friendly is the relationship for cancer patients? [J].

Aggarwal, Bharat B. ;

Gehlot, Prashasnika .

CURRENT OPINION IN PHARMACOLOGY, 2009, 9 (04) :351-369

[9] Exercise stimulates Pgc-1α transcription in skeletal muscle through activation of the p38 MAPK pathway [J].

Akimoto, T ;

Pohnert, SC ;

Li, P ;

Zhang, M ;

Gumbs, C ;

Rosenberg, PB ;

Williams, RS ;

Yan, Z .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (20) :19587-19593

[10] AP-1 dimers regulate transcription of the p14/p19ARF tumor suppressor gene [J].

Ameyar-Zazoua, M ;

Wisniewska, MB ;

Bakiri, L ;

Wagner, EF ;

Yaniv, M ;

Weitzman, JB .

ONCOGENE, 2005, 24 (14) :2298-2306

← 1 2 3 4 5 6 7 8 9 10 →