Glycemic control in patients with insulinoma

被引：33
作者：
Matej, Agata [1 ]
Bujwid, Hanna [2 ]
Wronski, Jakub [3 ]
机构：
[1] Prof W Orlowski Hosp, Warsaw, Poland
[2] Wolski Hosp, Warsaw, Poland
[3] Warsaw Med Univ, Dept Disaster Med, Warsaw, Poland
来源：
HORMONES-INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM | 2016年 / 15卷 / 04期
关键词：
Insulinoma; Glycemic control; Hypoglycemia; Hyperinsulinism; Pharmacotherapy; PANCREATIC NEUROENDOCRINE TUMORS; ENETS CONSENSUS GUIDELINES; MALIGNANT INSULINOMA; METASTATIC INSULINOMA; MEDICAL-TREATMENT; MANAGEMENT; HYPOGLYCEMIA; EVEROLIMUS; DIAZOXIDE; THERAPY;
D O I：
10.14310/horm.2002.1706
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Insulinoma is the most common neuroendocrine tumor of the pancreas. Surgical management of insulinomas is considered to be the only curative method. However, effective glycemic control preoperatively and in unresectable insulinomas remains a significant issue. Hyperinsulinism, occurring as a result of the hormone-secreting tumor, leads to life-threatening hypoglycemia episodes which require urgent medical treatment. This article discusses current management of hypoglycemia in insulinoma patients, including: education and lifestyle modifications, pharmacotherapy (diazoxide, somatostatin analogs, mTOR inhibitor - everolimus), cytoreductive methods and continuous glucose monitoring systems.
引用
收藏
页码：489 / 499
页数：11
相关论文
共 50 条
  • [41] Nursing home patients with diabetes: Prevalence, drug treatment and glycemic control
    Andreassen, Lillan Mo
    Sandberg, Sverre
    Kristensen, Gunn Berit Berge
    Solvik, Una Orvim
    Kjome, Reidun Lisbet Skeide
    [J]. DIABETES RESEARCH AND CLINICAL PRACTICE, 2014, 105 (01) : 102 - 109
  • [42] Pediatric Intensivists and Glycemic Control: Learning as We Go?
    Rigby, Mark R.
    [J]. PEDIATRIC CRITICAL CARE MEDICINE, 2013, 14 (02) : 221 - 222
  • [43] Inpatient Glycemic Control With Sliding Scale Insulin in Noncritical Patients With Type 2 Diabetes: Who Can Slide?
    Migdal, Alexandra L.
    Fortin-Leung, Charlie
    Pasquel, Francisco
    Wang, Heqiong
    Peng, Limin
    Umpierrez, Guillermo E.
    [J]. JOURNAL OF HOSPITAL MEDICINE, 2021, 16 (08) : 462 - 468
  • [44] Improved outcome of patients with diabetes mellitus with good glycemic control in the cardiac intensive care unit: a retrospective study
    Sharif, Kassem
    Ghadir, Suheil
    Jakubowicz, Daniela
    Amital, Howard
    Bragazzi, Nicola Luigi
    Watad, Abdulla
    Wainstein, Julio
    Bar-Dayan, Yosefa
    [J]. CARDIOVASCULAR DIABETOLOGY, 2019, 18 (1)
  • [45] Analysis of 55 patients with multiple endocrine neoplasia type 1-associated insulinoma from a single center in China
    Zhao, Yuan
    Yu, Jie
    Liu, Yiwen
    Lyu, Lu
    Ping, Fan
    Xu, Lingling
    Li, Wei
    Wang, Ou
    Xu, Qiang
    Wu, Wenming
    Zhang, Huabing
    Li, Yuxiu
    [J]. ORPHANET JOURNAL OF RARE DISEASES, 2022, 17 (01)
  • [46] Glycemic control in patients with diabetes mellitus on hemodialysis
    Lobanova, K. G.
    Severina, A. S.
    Martinov, S. A.
    Shamkhalova, M. Sh
    Shestakova, M., V
    [J]. TERAPEVTICHESKII ARKHIV, 2019, 91 (10) : 124 - 134
  • [47] Glycemic Control in Hospitalized Stroke Patients: A Review
    Patel, Vishal N.
    Kuo, Emory
    [J]. CURRENT DIABETES REPORTS, 2021, 21 (11)
  • [48] Preoperative treatment of benign insulinoma: diazoxide or somatostatin analogues?
    Gilliaux, Quentin
    Bertrand, Claude
    Hanon, Francois
    Donckier, Julian E.
    [J]. ACTA CHIRURGICA BELGICA, 2022, 122 (02) : 136 - 139
  • [49] Giant Insulinoma A Report of 3 Cases and Review of the Literature
    Callacondo, David
    Arenas, Jose L.
    Ganoza, Armando J.
    Rojas-Camayo, Jose
    Quesada-Olarte, Jose
    Robledo, Hernan
    [J]. PANCREAS, 2013, 42 (08) : 1323 - 1332
  • [50] Precision Glycemic Control in the ICU
    Marik, Paul E.
    [J]. CRITICAL CARE MEDICINE, 2016, 44 (07) : 1433 - 1434
12345