Noncanonical Translation Initiation Comes of Age

被引：4

作者：

Babitzke, Paul ^{[1
]}

O'Connor, Michael ^{[2
]}

机构：

[1] Penn State Univ, Dept Biochem & Mol Biol, Ctr RNA Mol Biol, University Pk, PA 16802 USA

[2] Univ Missouri, Sch Biol Sci, Kansas City, MO 64110 USA

来源：

JOURNAL OF BACTERIOLOGY | 2017年 / 199卷 / 14期

基金：

美国国家卫生研究院;

关键词：

ESCHERICHIA-COLI; MESSENGER-RNA; BINDING-SITES; SEQUENCE; ENHANCEMENT; DEGRADATION; MECHANISMS; EVOLUTION; GENES;

D O I：

10.1128/JB.00295-17

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The canonical translation initiation mechanism involves base pairing between the mRNA and 16S rRNA. However, a variety of identified mechanisms deviate from this conventional route. Beck and Janssen (J Bacteriol 199: e00091-17, 2017, https://doi.org/10.1128/JB.00091-17) have recently described another noncanonical mode of translation initiation. Here, we describe how this process differs from previously reported mechanisms, with the hope that it will foster increased awareness of the diversity of regulatory mechanisms that await discovery.

引用

页数：4

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