Noncanonical Translation Initiation Comes of Age

被引：4

作者：

Babitzke, Paul ^{[1
]}

O'Connor, Michael ^{[2
]}

机构：

[1] Penn State Univ, Dept Biochem & Mol Biol, Ctr RNA Mol Biol, University Pk, PA 16802 USA

[2] Univ Missouri, Sch Biol Sci, Kansas City, MO 64110 USA

来源：

JOURNAL OF BACTERIOLOGY | 2017年 / 199卷 / 14期

基金：

美国国家卫生研究院;

关键词：

ESCHERICHIA-COLI; MESSENGER-RNA; BINDING-SITES; SEQUENCE; ENHANCEMENT; DEGRADATION; MECHANISMS; EVOLUTION; GENES;

D O I：

10.1128/JB.00295-17

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The canonical translation initiation mechanism involves base pairing between the mRNA and 16S rRNA. However, a variety of identified mechanisms deviate from this conventional route. Beck and Janssen (J Bacteriol 199: e00091-17, 2017, https://doi.org/10.1128/JB.00091-17) have recently described another noncanonical mode of translation initiation. Here, we describe how this process differs from previously reported mechanisms, with the hope that it will foster increased awareness of the diversity of regulatory mechanisms that await discovery.

引用

页数：4

共 25 条

[1] Inability of Prevotella bryantii to Form a Functional Shine-Dalgarno Interaction Reflects Unique Evolution of Ribosome Binding Sites in Bacteroidetes [J].

Accetto, Tomaz ;

Avgustin, Gorazd .

PLOS ONE, 2011, 6 (08)

[2] The critical role of RNA processing and degradation in the control of gene expression [J].

Arraiano, Cecilia M. ;

Andrade, Jose M. ;

Domingues, Susana ;

Guinote, Ines B. ;

Malecki, Michal ;

Matos, Rute G. ;

Moreira, Ricardo N. ;

Pobre, Vania ;

Reis, Filipa P. ;

Saramago, Margarida ;

Silva, Ines J. ;

Viegas, Sandra C. .

FEMS MICROBIOLOGY REVIEWS, 2010, 34 (05) :883-923

[3] Novel Translation Initiation Regulation Mechanism in Escherichia coli ptrB Mediated by a 5′-Terminal AUG [J].

Beck, Heather J. ;

Janssen, Gary R. .

JOURNAL OF BACTERIOLOGY, 2017, 199 (14)

[4] 5′-Terminal AUGs in Escherichia coli mRNAs with Shine-Dalgarno Sequences: Identification and Analysis of Their Roles in Non-Canonical Translation Initiation [J].

Beck, Heather J. ;

Fleming, Ian M. C. ;

Janssen, Gary R. .

PLOS ONE, 2016, 11 (07)

[5] Analysis of SD sequences in completed microbial genomes: Non-SD-led genes are as common as SD-led genes [J].

Chang, Bill ;

Halgamuge, Saman ;

Tang, Sen-Lin .

GENE, 2006, 373 :90-99

[6] Translational standby sites: How ribosomes may deal with the rapid folding kinetics of mRNA [J].

de Smit, MH ;

van Duin, J .

JOURNAL OF MOLECULAR BIOLOGY, 2003, 331 (04) :737-743

[7] Occlusion of the Ribosome Binding Site Connects the Translational Initiation Frequency, mRNA Stability and Premature Transcription Termination [J].

Eriksen, Mette ;

Sneppen, Kim ;

Pedersen, Steen ;

Mitarai, Namiko .

FRONTIERS IN MICROBIOLOGY, 2017, 8

[8] THE EFFECT OF RIBOSOMAL PROTEIN-S1 FROM ESCHERICHIA-COLI AND MICROCOCCUS-LUTEUS ON PROTEIN-SYNTHESIS INVITRO BY ESCHERICHIA-COLI AND BACILLUS-SUBTILIS [J].

FARWELL, MA ;

ROBERTS, MW ;

RABINOWITZ, JC .

MOLECULAR MICROBIOLOGY, 1992, 6 (22) :3375-3383

[9] Initiation of mRNA translation in bacteria: structural and dynamic aspects [J].

Gualerzi, Claudio O. ;

Pon, Cynthia L. .

CELLULAR AND MOLECULAR LIFE SCIENCES, 2015, 72 (22) :4341-4367

[10] Leveraging genome-wide datasets to quantify the functional role of the anti-Shine-Dalgarno sequence in regulating translation efficiency [J].

Hockenberry, Adam J. ;

Pah, Adam R. ;

Jewett, Michael C. ;

Amaral, Luis A. N. .

OPEN BIOLOGY, 2017, 7 (01)

← 1 2 3 →