Ethynyl MIDA boronate: a readily accessible and highly versatile building block for small molecule synthesis

被引：68

作者：

Struble, Justin R. ^{[1
]}

Lee, Sul Joong ^{[1
]}

Burke, Martin D. ^{[1
]}

机构：

[1] Univ Illinois, Dept Chem, Howard Hughes Med Inst, Roger Adams Lab, Urbana, IL 61801 USA

来源：

TETRAHEDRON | 2010年 / 66卷 / 26期

基金：

美国国家科学基金会;

关键词：

MIDA boronates; Iterative cross-coupling; Small molecule synthesis; Alkynes Sonogashira coupling; Diels-Alder; CROSS-COUPLING REACTIONS; ORGANOBORON CHEMISTRY; RADICAL REACTIONS; ESTERS; ACIDS; DERIVATIVES; EFFICIENT; STRATEGY; COMPLEX; SCOPE;

D O I：

10.1016/j.tet.2010.04.020

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ethynyl N-methyliminodiacetic acid (MIDA) boronate is a very useful building block for small molecule synthesis. This compound can serve as both a bifunctional acetylene equivalent with the capacity for terminus-selective bis-functionalization and a versatile starting material for the preparation of a wide range of other MIDA boronate building blocks. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：4710 / 4718

页数：9

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