Neuromyelitis optica (Devic's disease) in a case of systemic lupus erythematosus with antiphospholipid antibodies: is there a role for anticoagulants?

被引：0
作者：
Charakidas, A
Brouzas, D
Perraki, A
Moschos, M
机构：
[1] Hippocrat Gen Hosp, Dept Ophthalmol, Athens, Greece
[2] Hop Jules Gonin, Lausanne, Switzerland
来源：
NEURO-OPHTHALMOLOGY | 2004年 / 28卷 / 04期
关键词：
Devic's disease; systemic lupus erythematosus; antiphospholipid antibodies;
D O I：
10.1080/01658100490887841
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We report a case of transverse myelitis and bilateral optic neuritis (neuromyelitis optica or Devic's disease) in a patient with systemic lupus erythematosus (SLE) and antiphospholipid antibodies. Investigation included neuroimaging, electrophysiology, visual fields, and determination of antiphospholipid antibodies. Devic's disease is an extremely rare manifestation of SLE and recent advances in the histopathologic understanding of this condition, including the disassociation from demyelination and a postulated link to vascular disease with axonal necrosis, suggest the implication of antiphospholipid antibodies in the pathophysiology of at least some cases of the disease and the potential favorable effect of anticoagulation.
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页码：179 / 181
页数：3
相关论文
共 5 条
[1]   Neurological manifestations of antiphospholipid antibody syndrome [J].
Brey, RL ;
Escalante, A .
LUPUS, 1998, 7 :S67-S74
[2]   Optic neuropathy in systemic lupus erythematosus and antiphospholipid syndrome (APS): Clinical features, pathogenesis, review of the literature and proposed ophthalmological criteria for APS diagnosis [J].
Giorgi, D ;
Gabrieli, CB .
CLINICAL RHEUMATOLOGY, 1999, 18 (02) :124-131
[3]   Transverse myelopathy in systemic lupus erythematosus: an analysis of 14 cases and review of the literature [J].
Kovacs, B ;
Lafferty, TL ;
Brent, LH ;
DeHoratius, RJ .
ANNALS OF THE RHEUMATIC DISEASES, 2000, 59 (02) :120-124
[4]  
LAVALLE C, 1990, J RHEUMATOL, V17, P34
[5]   The clinical course of neuromyelitis optica (Devic's syndrome) [J].
Wingerchuk, DM ;
Hogancamp, WF ;
O'Brien, PC ;
Weinshenker, BG .
NEUROLOGY, 1999, 53 (05) :1107-1114
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