Effect of cholesterol on the phase state and permeability of mixed liposomes composed of anionic diphosphatidylglycerol and zwitterionic dipalmitoylphosphatidylcholine

被引:15
|
作者
Efimova, Anna A. [1 ]
Kostenko, Stepan N. [1 ]
Orlov, Viktor N. [2 ]
Yaroslavov, Alexander A. [1 ]
机构
[1] Moscow MV Lomonosov State Univ, Dept Chem, Moscow 119991, Russia
[2] Moscow MV Lomonosov State Univ, Res Inst Physicochem Biol, Moscow 119991, Russia
基金
俄罗斯科学基金会; 俄罗斯基础研究基金会;
关键词
DRUG-DELIVERY; CLINICAL-APPLICATIONS; LIPID-BILAYERS; STABILITY; MEMBRANES; BEHAVIOR; SYSTEMS;
D O I
10.1016/j.mencom.2016.03.003
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The incorporation of cholesterol into a solid liposomal membrane makes the membrane liquid with a higher lipid mobility (a lower microviscosity) and suppresses the membrane permeability toward inorganic ions.
引用
收藏
页码:99 / 100
页数:2
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