Effect of cholesterol on the phase state and permeability of mixed liposomes composed of anionic diphosphatidylglycerol and zwitterionic dipalmitoylphosphatidylcholine

被引：15

作者：

Efimova, Anna A. ^{[1
]}

Kostenko, Stepan N. ^{[1
]}

Orlov, Viktor N. ^{[2
]}

Yaroslavov, Alexander A. ^{[1
]}

机构：

[1] Moscow MV Lomonosov State Univ, Dept Chem, Moscow 119991, Russia

[2] Moscow MV Lomonosov State Univ, Res Inst Physicochem Biol, Moscow 119991, Russia

来源：

MENDELEEV COMMUNICATIONS | 2016年 / 26卷 / 02期

基金：

俄罗斯科学基金会; 俄罗斯基础研究基金会;

关键词：

DRUG-DELIVERY; CLINICAL-APPLICATIONS; LIPID-BILAYERS; STABILITY; MEMBRANES; BEHAVIOR; SYSTEMS;

D O I：

10.1016/j.mencom.2016.03.003

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The incorporation of cholesterol into a solid liposomal membrane makes the membrane liquid with a higher lipid mobility (a lower microviscosity) and suppresses the membrane permeability toward inorganic ions.

引用

页码：99 / 100

页数：2

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