Rotavirus Entry: a Deep Journey into the Cell with Several Exits

被引:75
作者
Arias, Carlos F. [1 ]
Silva-Ayala, Daniela [1 ]
Lopez, Susana [1 ]
机构
[1] Univ Nacl Autonoma Mexico, Inst Biotecnol, Cuernavaca 62191, Morelos, Mexico
关键词
MA104; CELLS; ENTER;
D O I
10.1128/JVI.01787-14
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Rotaviruses are the leading etiological agents of acute gastroenteritis in infants and young children worldwide. These nonenveloped viruses enter cells using different types of endocytosis and, depending on the virus strain, travel to different endosomal compartments before exiting to the cytosolic space. In this Gem, we review the viral and cellular factors involved in the different stages of a productive virus cell entry and share with the readers the journey that we have taken into the cell to learn about virus entry.
引用
收藏
页码:890 / 893
页数:4
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