Regio- and enantioselective siloxybutylation at the more hindered α-site of unsymmetrical ketone using chiral aluminum trisnaphthoxide

被引：0

作者：

Saito, S ^{[1
]}

Nakadai, M ^{[1
]}

Yamamoto, H ^{[1
]}

机构：

[1] Nagoya Univ, Japan Sci & Technol Corp, CREST, Grad Sch Engn, Nagoya, Aichi 4648603, Japan

来源：

SYNLETT | 2000年 / 08期

关键词：

alkylations; aluminum; asymmetric synthesis; ketones;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A regio- and enantioselective siloxybutylation at the more hindered alpha-site of unsymmetrical dialkyl ketones was achieved to give a quarternary carbon center by the combined use of the chiral aluminum trisnaphthoxide (R)-ATBN and a base.

引用

页码：1107 / 1110

页数：4

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