Extensive enteric leiomyolysis due to cytomegalovirus enterocolitis in vertically acquired human immunodeficiency virus infection in infants

被引：7
作者：
Smith, VV
Williams, AJ
Novelli, V
Malone, M
机构：
[1] Great Ormond St Hosp Children NHS Trust, Camelia Botnar Labs, Dept Histopathol, London WC1N 3JH, England
[2] Great Ormond St Hosp Children NHS Trust, Dept Infect Dis, London WC1N 3JH, England
来源：
PEDIATRIC AND DEVELOPMENTAL PATHOLOGY | 2000年 / 3卷 / 06期
关键词：
cytomegalovirus; colitis; enteritis; human immunodeficiency virus; infants; leiomyolysis;
D O I：
10.1007/s100240010109
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
We report two infants with the acquired immunodeficiency syndrome (AIDS) and rectal bleeding due to cytomegalovirus (CMV) ileitis and colitis with minimal focal mucosal ulceration but with extensive leiomyolysis of the muscularis propria. Immunostaining and in situ hybridization for CMV showed numerous viral inclusions in the myocytes of the muscularis propria and vascular endothelium/smooth muscle with only occasional inclusions present in the muscularis mucosae. Colectomy was curative in one patient; in the other the bowel was only examined at postmortem.
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页码：591 / 596
页数：6
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