A Case of Adult Intestinal Toxemia Botulism During Prolonged Hospitalization in an Allogeneic Hematopoietic Cell Transplant Recipient

被引：7

作者：

Parameswaran, Lalitha ^{[1
]}

Rao, Agam ^{[2
]}

Chastain, Katherine ^{[3
]}

Ackelsburg, Joel ^{[4
]}

Adams, Eleanor ^{[5
]}

Jackson, Brendan ^{[2
]}

Voigt, Louis P. ^{[6
]}

Chen, Xi ^{[7
,8
]}

Boulad, Farid ^{[3
,8
]}

Taur, Ying ^{[1
,8
,9
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Dept Med, Infect Dis Serv, New York, NY 10021 USA

[2] Ctr Dis Control & Prevent, Enter Dis Epidemiol Branch, Div Foodborne Waterborne & Environm Dis, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA USA

[3] Mem Sloan Kettering Canc Ctr, Dept Pediat, Bone Marrow Transplantat Serv, 1275 York Ave, New York, NY 10021 USA

[4] Bur Communicable Dis, New York City Dept Hlth & Mental Hyg, New York, NY USA

[5] New York State Dept Hlth, Albany, NY USA

[6] Mem Sloan Kettering Canc Ctr, Dept Med, Crit Care Med Serv, 1275 York Ave, New York, NY 10021 USA

[7] Mem Sloan Kettering Canc Ctr, Dept Neurol, 1275 York Ave, New York, NY 10021 USA

[8] Weill Cornell Med Coll, New York, NY USA

[9] Mem Sloan Kettering Canc Ctr, Lucille Castori Ctr Microbes Inflammat & Canc, 1275 York Ave, New York, NY 10021 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2018年 / 66卷

关键词：

botulism; microbiota; bone marrow transplant; adult intestinal toxemia botulism; 16S rRNA gene sequencing; COLONIZATION; TRACT;

D O I：

10.1093/cid/cix847

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We report a laboratory-confirmed case of adult intestinal toxemia botulism in an allogeneic hematopoietic stem cell transplantation (allo-HCT) recipient. Onset of symptoms occurred within the hospitalized setting, making this case particularly unique. Botulism may have arisen because of significant intestinal disruption and compromise, and not directly from immune compromise.

引用

页码：S99 / S102

页数：4

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