High-sensitivity optical biosensor based on cascaded Mach-Zehnder interferometer and ring resonator using Vernier effect

被引：74

作者：

Jiang, Xianxin ^{[1
]}

Chen, Yangqing ^{[1
]}

Yu, Fang ^{[1
]}

Tang, Longhua ^{[1
]}

Li, Mingyu ^{[1
]}

He, Jian-Jun ^{[1
]}

机构：

[1] Zhejiang Univ, Dept Opt Engn, Ctr Integrated Optoelect, State Key Lab Modern Opt Instrumentat, Hangzhou 310027, Zhejiang, Peoples R China

来源：

OPTICS LETTERS | 2014年 / 39卷 / 22期

基金：

国家高技术研究发展计划(863计划);

关键词：

SILICON; SENSORS; SURFACE; ARRAY;

D O I：

10.1364/OL.39.006363

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We demonstrate an ultrahigh sensitivity silicon photonic biosensor based on cascaded Mach-Zehnder interferometer (MZI) and ring resonator with the Vernier effect using wavelength interrogation. Experimental results show that the sensitivities reached 2870 nm/RIU and 21,500 nm/RIU for MZI sensor and MZI-ring sensor, respectively. A biosensing application was demonstrated by monitoring the interaction between goat and antigoat immunoglobulin G (IgG) pairs. The measured results show that 1 ng/ml IgG resulted in 0.035 nm and 0.5 nm wavelength shift for MZI sensor and MZI-ring sensor, respectively. This high performance sensor is promising for medical diagnostic applications. (C) 2014 Optical Society of America

引用

页码：6363 / 6366

页数：4

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