DNA-dependent protein kinase (DNA-PK) phosphorylates and activates TonEBP/NFAT5 in response to hypertonicity

被引:0
|
作者
Lee, SD
Colla, E
Park, WK
Chen, DJ
Kwon, HM
机构
[1] Univ Maryland, Baltimore, MD 21201 USA
[2] Lawrence Berkeley Natl Lab, Div Life Sci, Berkeley, CA USA
来源
FASEB JOURNAL | 2003年 / 17卷 / 04期
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:A482 / A482
页数:1
相关论文
共 50 条
  • [31] Preclinical characterization of the selective DNA-dependent protein kinase (DNA-PK) inhibitor VX-984 in combination with chemotherapy
    Boucher, D.
    Hillier, S.
    Newsome, D.
    Wang, Y.
    Takemoto, D.
    Gu, Y.
    Markland, W.
    Hoover, R.
    Arimoto, R.
    Maxwell, J.
    Fields, S. Z.
    Charifson, P.
    Penney, M. S.
    Tanner, K.
    ANNALS OF ONCOLOGY, 2016, 27
  • [32] The DNA-activated protein kinase - DNA-PK
    Anderson, CW
    Carter, TH
    MOLECULAR ANALYSIS OF DNA REARRANGEMENTS IN THE IMMUNE SYSTEM, 1996, 217 : 91 - 111
  • [33] DNA ligase I activation during repair of alkylation damaged DNA is via DNA-dependent protein kinase (DNA-PK) mediated phosphorylation
    Bhat, KR
    Benton, BJ
    Ray, R
    FASEB JOURNAL, 1999, 13 (07): : A1453 - A1453
  • [34] A novel, selective inhibitor of DNA-dependent protein kinase (DNA-PK) potentiates the effects of DNA-damaging therapies in hepatocellular carcinoma
    Willoughby, Catherine E.
    Thomas, Huw D.
    Rennison, Tommy
    Cano, Celine
    Reeves, Helen L.
    Wedge, Stephen R.
    CANCER RESEARCH, 2017, 77
  • [35] Visualizing functional dynamicity in the DNA-dependent protein kinase holoenzyme DNA-PK complex by integrating SAXS with cryo-EM
    Hammel, Michal
    Rosenberg, Daniel J.
    Bierma, Jan
    Hura, Gregory L.
    Thapar, Roopa
    Lees-Miller, Susan P.
    Tainer, John A.
    PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 2021, 163 : 74 - 86
  • [36] Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes
    Shao, RG
    Cao, CX
    Zhang, HL
    Kohn, KW
    Wold, MS
    Pommier, Y
    EMBO JOURNAL, 1999, 18 (05): : 1397 - 1406
  • [37] DNA-Dependent Protein Kinase (DNA-PK) Regulates TNF-Induced VCAM-1 Expression Independently of its Function in DNA Repair: A Novel Role of DNA-PK and its Involvement in Athrogenesis
    Ju, Jihang
    Kim, Hogyoung
    Naura, Amarjit S.
    Wilk, Anna M.
    Reiss, Krzysztof
    Strong, Jack
    Boulares, Hamid A.
    CIRCULATION, 2012, 126 (21)
  • [38] Enhancing Standard of Care Chemotherapy Efficacy Using DNA-Dependent Protein Kinase (DNA-PK) Inhibition in Preclinical Models of Ewing Sarcoma
    Collins, Victor J.
    Ludwig, Katelyn R.
    Nelson, Ariana E.
    Rajan, Soumya Sundara
    Yeung, Choh
    Vulikh, Ksenia
    Isanogle, Kristine A.
    Mendoza, Arnulfo
    Difilippantonio, Simone
    Karim, Baktiar O.
    Caplen, Natasha J.
    Heske, Christine M.
    MOLECULAR CANCER THERAPEUTICS, 2024, 23 (08) : 1109 - 1123
  • [39] Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries
    Leahy, JJJ
    Golding, BT
    Griffin, RJ
    Hardcastle, IR
    Richardson, C
    Rigoreau, L
    Smith, GCM
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2004, 14 (24) : 6083 - 6087
  • [40] Mapping the ATP-binding domain of DNA-dependent protein kinase (DNA-PK) with coumarin- and isocoumarin-derived inhibitors
    Payne, Sara L.
    Rodriguez-Aristegui, Sonsoles
    Bardos, Julia
    Cano, Celine
    Golding, Bernard T.
    Hardcastle, Ian R.
    Peacock, Marcus
    Parveen, Nahida
    Griffin, Roger J.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (12) : 3649 - 3653