Depth of Interaction Measurements Based on Rectangular Light Sharing Window Technology and Nine-Crystals-to-One-SiPM Coupling Method

被引：4

作者：

Zhang, Xi ^{[1
]}

Ye, Baihezi ^{[1
]}

Yu, Hongsen ^{[1
]}

Zhang, Yuyu ^{[1
]}

Xie, Siwei ^{[2
]}

Xu, Jianfeng ^{[1
]}

Peng, Qiyu ^{[3
,4
]}

机构：

[1] Huazhong Univ Sci & Technol, Sch Mech Sci & Engn, Wuhan 430074, Peoples R China

[2] Pitech Co, Shenzhen 518000, Peoples R China

[3] Shenzhen Bay Lab, Inst Biomed Engn, Shenzhen 518132, Peoples R China

[4] Lawrence Berkeley Natl Lab, Dept Mol Biophys & Integrated Bioimaging, Berkeley, CA 94720 USA

来源：

IEEE TRANSACTIONS ON RADIATION AND PLASMA MEDICAL SCIENCES | 2021年 / 5卷 / 03期

基金：

中国国家自然科学基金;

关键词：

Crystals; Detectors; Optical detectors; Photonics; Biomedical optical imaging; Optical reflection; Decoding; Depth of interaction (DOI); light sharing window; optical simulation; positron emission tomography (PET) detector; 4-LAYER DOI DETECTOR; PET DETECTOR; CLINICAL-APPLICATIONS; RELATIVE OFFSET; MONOLITHIC LYSO; CRYSTAL ARRAY; PERFORMANCE; DESIGN; SIPM; SIMULATION;

D O I：

10.1109/TRPMS.2020.3023073

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Depth of interaction (DOI) decoding capability shows great application potential for positron emission tomography (PET), especially for high-resolution small-animal PET or long axial field of view PET systems. On the basis of GATE optical simulation results, we presented a novel 9 x 9 lutetium-yttrium oxyorthosilicate array with 10-mm rectangular light-sharing windows (RLSWs) and assembly the detector with nine crystals coupled to one silicon photomultiplier (SiPM) method; this caused DOI-related position shifts in the crystal decoding spots of the flood map. Homogeneous radiation was used to establish transfer functions to convert spot shifts into DOI measurements. The conventional collimated radiation experiments were used to assess the accuracy of the DOI measurements. Flood map results show that 81 segmented crystals can be clearly resolved, including 16 crystals adjacent to two RLSW windows (M-type), 40 crystals adjacent to one RLSW window (E-type), and 25 crystals not adjacent to any RLSW window (C-type). The mean absolute error of all DOI-capable crystals, M-type crystals, and E-type crystals are 2.15 +/- 0.61, 1.95 +/- 0.50, and 2.23 +/- 0.63 mm, respectively. The novel nine-crystals-to-one-SiPM coupling technology is a low cost approach for constructing high-performance DOI detector modules. Detectors using nine-crystals-to-one-SiPM coupling technology are good candidates for high-resolution preclinical PET and for total-body PET.

引用

页码：306 / 314

页数：9