Nucleosides and nucleotides.: 165.: Chemical ligation of oligodeoxynucleotides having a mercapto group at the 5-position of 2′-deoxyuridine via a disulfide bond

被引：6

作者：

Ueno, Y ^{[1
]}

Nakagawa, A ^{[1
]}

Matsuda, A ^{[1
]}

机构：

[1] Hokkaido Univ, Fac Pharmaceut Sci, Kita Ku, Sapporo, Hokkaido 060, Japan

来源：

NUCLEOSIDES & NUCLEOTIDES | 1998年 / 17卷 / 1-3期

关键词：

D O I：

10.1080/07328319808005176

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We describe the nonenzymatic ligation of oligodeoxynucleotides (ODNs) containing a mercapto group at the 5 position of 2'-deoxyuridine via a disulfide bond. Two ODNs containing different sequences were efficiently ligated in the presence of a template by this method.

引用

页码：283 / 289

页数：7

共 24 条

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