A Case of Erythroplasia of Queyrat Treated with Imiquimod 5% Cream and Excision

被引：15

作者：

Choi, Jee Woong ^{[1
]}

Choi, Mira ^{[1
]}

Cho, Kwang Hyun ^{[1
]}

机构：

[1] Seoul Natl Univ, Coll Med, Dept Dermatol, Seoul 110744, South Korea

来源：

ANNALS OF DERMATOLOGY | 2009年 / 21卷 / 04期

关键词：

Erythroplasia of Queyrat; Imiquimod; BOWENS-DISEASE; PAPILLOMAVIRUSES; CARCINOMA; CANCER;

D O I：

10.5021/ad.2009.21.4.419

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Imiquimod is a new immunomodulating agent with antitumor and antiviral properties that has been shown to be clinically effective in various kinds of skin diseases, including precancerous dermatoses. Erythroplasia of Queyrat is a carcinoma in situ that mainly occurs on the glans penis. There are several non-invasive treatment options for erythroplasia of Queyrat such as photodynamic therapy, cryosurgery and applying various kinds of topical agents. We now report a case of typical erythroplasia of Queyrat on glans penis associated with human papillomavirus type 16 infection that was treated by imiquimod 5% cream and the subsequent excision of an imiquimod-resistant penile lesion. (Ann Dermatol 21(4) 419 similar to 422, 2009)

引用

页码：419 / 422

页数：4

共 14 条

[1] Treatment of Bowen's disease and erythroplasia of Queyrat [J].

Arlette, JP .

BRITISH JOURNAL OF DERMATOLOGY, 2003, 149 :43-47

[2]

GRAHAM JH, 1973, CANCER-AM CANCER SOC, V32, P1396, DOI 10.1002/1097-0142(197312)32:6<1396::AID-CNCR2820320618>3.0.CO

[3]

2-T

[4] Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway [J].

Hemmi, H ;

Kaisho, T ;

Takeuchi, O ;

Sato, S ;

Sanjo, H ;

Hoshino, K ;

Horiuchi, T ;

Tomizawa, H ;

Takeda, K ;

Akira, S .

NATURE IMMUNOLOGY, 2002, 3 (02) :196-200

[5] CARCINOMA ARISING IN BOWENS DISEASE [J].

KAO, GF .

ARCHIVES OF DERMATOLOGY, 1986, 122 (10) :1124-1126

[6]

Meyer T, 2001, CANCER DETECT PREV, V25, P533

[7] Erythroplasia of Queyrat treated with imiquimod 5% cream [J].

Micali, Giuseppe ;

Nasca, Maria Rita ;

De Pasquale, Rocco .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2006, 55 (05) :901-903

[8] CANCERS, PRE-CANCERS, AND PSEUDO-CANCERS ON THE MALE GENITALIA - A REVIEW OF CLINICAL APPEARANCES, HISTOPATHOLOGY, AND MANAGEMENT [J].

MIKHAIL, GR .

JOURNAL OF DERMATOLOGIC SURGERY AND ONCOLOGY, 1980, 6 (12) :1027-1035

[9] Imiquimod applied topically: a novel immune response modifier and new class of drug [J].

Miller, RL ;

Gerster, JF ;

Owens, ML ;

Slade, HB ;

Tomai, MA .

INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY, 1999, 21 (01) :1-14

[10] Topical imiquimod - A review of its use in genital warts [J].

Perry, CM ;

Lamb, HM .

DRUGS, 1999, 58 (02) :375-390

← 1 2 →