Probiotics to Prevent Clostridium difficile Infection in Patients Receiving Antibiotics

被引：72

作者：

Goldenberg, Joshua Z. ^{[1
,2
]}

Mertz, Dominik ^{[3
]}

Johnston, Bradley C. ^{[4
]}

机构：

[1] Bastyr Univ, Res Inst, Kenmore, WA USA

[2] Univ Technol Sydney, Australian Res Ctr Complementary & Integrat Med, Ultimo, Australia

[3] McMaster Univ, Dept Med, Div Infect Dis, Hamilton, ON, Canada

[4] Dalhousie Univ, Fac Med, Dept Community Hlth & Epidemiol, Halifax, NS, Canada

来源：

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION | 2018年 / 320卷 / 05期

关键词：

ADULTS;

D O I：

10.1001/jama.2018.9064

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

CLINICAL QUESTION In adults and children prescribed antibiotics, is co-administration of a probiotic associated with a lower risk of symptomatic Clostridium difficile infection without an increase in adverse events? BOTTOM LINE Moderate-quality evidence suggests that probiotics are associated with a lower risk of C difficile infection and very low-quality evidence suggests that probiotics are associated with fewer adverse events vs placebo or no treatment.

引用

页码：499 / 500

页数：2

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